Diagnosis of chronic rhinosinusitis in patients with cystic fibrosis: correlation between anamnesis, nasal endoscopy and computed tomography

Abstract

The diagnosis of chronic rhinosinusitis was statistically different between the three methods. It was higher in imaging analysis and lower in questionnaire. The nasal endoscopy is an excellent method to evaluate nasossinusal disease in cystic fibrosis.

Nasal and paranasal sinus endoscopy, computed tomography and microbiology of upper airways and the correlations with genotype and severity of cystic fibrosis

“…Nasal and paranasal sinus CT scan revealed high prevalence of affections, in which 49 out of 50 patients presented at least one affection. These data are in accordance with other studies that assessed CT scan findings in CF patients [4,6,7,12,14]. However, few studies have correlated the abnormalities found in upper airway CT scans with genotype and severity of the disease.…”

“…The prevalence of this finding is about 57% [12,14,15], quite close to our prevalence data of 58%. It is not clear whether bulging corresponds to pseudomucocele, detected by paranasal sinuses CT scan.…”

“…Nasal and paranasal endoscopic studies evidenced the following findings in CF patients: presence of polyposis, middle meatus secretion and nasal lateral wall bulging [1][2][3][4][5][6][7]11,12]. In our study, 18/50 (36%) of the patients presented nasal polyposis, 16 of them younger than 15 years.…”

Imaging evalution of the gingival fibromatosis and dental abnormalities syndrome

“…In asymptomatic adult patients, Havas et al, 25 evaluating CT scans of the skull, found 42% of abnormalities in 1 or more paranasal sinus and the thickness growth of the mucosa of the ethmoidal sinus was the alteration more frequently identified. In studies with patients aged from 6 years to 22 years, Boari and Castro Jú nior 26 found radiographic opacification of the paranasal sinus in 93% of the cases; only 20% were symptomatic, and they concluded that diagnosis of the chronic rhinosinusitis was superior in the analyses carried out through image exam in relation to anamnese. The causes of mucosa thickness growth or a b 26 or by another factor that has led to the inflammation of the mucosa, such as asthma, rhinitis, chemical products and viral or bacterial infections.…”

“…In studies with patients aged from 6 years to 22 years, Boari and Castro Jú nior 26 found radiographic opacification of the paranasal sinus in 93% of the cases; only 20% were symptomatic, and they concluded that diagnosis of the chronic rhinosinusitis was superior in the analyses carried out through image exam in relation to anamnese. The causes of mucosa thickness growth or a b 26 or by another factor that has led to the inflammation of the mucosa, such as asthma, rhinitis, chemical products and viral or bacterial infections. 27 The fact that the patients belong to the same family and coexist in one environment may justify the fact that all present alterations are in the paranasal sinuses.…”