Diagnosis of Coxsackie Enterovirus Infections by Serum Complement Fixation Tests

We describe two previously healthy children who were hospitalized in the same period in different departments of our University with clinical signs of Kawasaki syndrome, which were treated with intravenous immunoglobulins and acetylsalicylic acid: in both cases, Coxsackie virus infection was concurrently demonstrated by enzyme-linked immunosorbent assay, and complement fixation test identified antibodies to serotype B3. In the acute phase, both patients presented hyperechogenic coronary arteries, but no cardiologic sequels in the mid term. The etiological relationship between Kawasaki syndrome and Coxsackie viruses is only hypothetical; however, the eventual identification of ad hoc environmental triggers is advisable in front of children with Kawasaki syndrome, with the aim of optimizing epidemiological surveillance and understanding the intimate biological events of this condition.

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Kawasaki syndrome and concurrent Coxsackie virus B3 infection

Rigante

Cantarini

Piastra

et al. 2010

Rheumatol Int

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Diagnosis of enterovirus (picornavirus) infections by the complement fixation test using a group picornavirus commercial antigen

Alexander¹

1982

Journal of Infection

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Diagnosis of Coxsackie Enterovirus Infections by Serum Complement Fixation Tests

Cited by 2 publications

References 4 publications

Kawasaki syndrome and concurrent Coxsackie virus B3 infection

Kawasaki syndrome and concurrent Coxsackie virus B3 infection

Diagnosis of enterovirus (picornavirus) infections by the complement fixation test using a group picornavirus commercial antigen

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