Diabetic Macula Edema (DME) is brought about by collection of extracellular liquid from hyper penetrable vessels inside the macula. DME is one of the main sources of visual impairment among diabetic patients. The patients who are influenced by diabetes and Diabetic Retinopathy (DR) are well on the way to be influenced by DME. The presence of Exudates in macula area is the significant sign of essence of DME. The Optic Disc (OD) and Blood Vessels (BVs) are the retinal milestones divided to find macula and fovea locale. Area of macula focus is vital for portion the anomalies in the macula locale. The irregularity and its seriousness of the sickness in macula district can be distinguished solely after finding the macula place. Pictures from High Resolution Fundus (HRF) database are utilized for testing and examination. The Atanassov’s Intuitionistic fuzzy Sets (A-FIS) and morphological tasks are utilized to portion OD and BVs. With these retinal landmarks, macula is recognized by raphe assessment. The Exudates (EXs) present in macula district are portioned proficiently by inclination based versatile thresholding. Deep Convolution neural network used for classification of DME and non-DME affected images. The division of OD and EXs has accomplished SE of 95.21%, 98.2%, SPE of 82.36%, 97.4% and ACC of 99.21%, 99.23% separately.