Diagnosis of Fungal Infections

Maertens, Johan; Marr, Kieren A.

doi:10.3109/9781420017182

Cited by 4 publications

(3 citation statements)

References 168 publications

(239 reference statements)

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“…This is consistent with current clinical practice, as well as a previous IAD study . Diagnosis of superficial fungal infection relies more heavily on clinical findings and less on laboratory support . Pressure injuries are a localised injury to the skin and/or underlying tissue, usually over a bony prominence, as a result of pressure, or pressure in combination with shear .…”

Section: Methodssupporting

confidence: 82%

“…According to Professor Jack Sobel (personal email, jsobel@med.wayne.edu, 3 April 2014), the fungal rash may also present as non‐specific, confluent and papular, creating some difficulty in clinical diagnosis. The presence of a secondary fungal infection would require treatment, but it is desirable to obtain a microbiological culture prior to commencing anti‐mycotic therapy Accordingly, the presence of a secondary fungal infection may have been under‐ or over‐estimated in our study. Our data showed that 32% (12/38) of patients with IAD demonstrated clinical evidence of a fungal infection.…”

Section: Discussionmentioning

confidence: 94%

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Incontinence‐associated dermatitis: a cross‐sectional prevalence study in the Australian acute care hospital setting

Campbell

Coyer

Osborne

2014

International Wound Journal

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The purpose of this cross-sectional study was to identify the prevalence of incontinence and incontinence-associated dermatitis (IAD) in Australian acute care patients and to describe the products worn to manage incontinence, and those provided at the bedside for perineal skin care. Data on 376 inpatients were collected over 2 days at a major Australian teaching hospital. The mean age of the sample group was 62 years and 52% of the patients were male. The prevalence rate of incontinence was 24% (91/376). Urinary incontinence was significantly more prevalent in females (10%) than males (6%) (χ(2) = 4·458, df = 1, P = 0·035). IAD occurred in 10% (38/376) of the sample group, with 42% (38/91) of incontinent patients having IAD. Semi-formed and liquid stool were associated with IAD (χ(2) = 5·520, df = 1, P = 0·027). Clinical indication of fungal infection was present in 32% (12/38) of patients with IAD. Absorbent disposable briefs were the most common incontinence aids used (80%, 70/91), with soap/water and disposable washcloths being the clean-up products most commonly available (60%, 55/91) at the bedside. Further data are needed to validate this high prevalence. Studies that address prevention of IAD and the effectiveness of management strategies are also needed.

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Section: Methodssupporting

confidence: 82%

Section: Discussionmentioning

confidence: 94%

Incontinence‐associated dermatitis: a cross‐sectional prevalence study in the Australian acute care hospital setting

Campbell

Coyer

Osborne

2014

International Wound Journal

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“…Despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagnosis (5). Several reasons are responsible for these limitations, such as non-specific and variable clinical symptoms that occur late in the course of disease, considerable delay in turn-around time due to slow growth of the fungus in culture, the time needed for its identification, and especially, a lack of diagnostic methods with sufficient sensitivity and specificity (6). Because of the limitations of the aforementioned diagnostic methods, non-culture methods based on the detection of the molecular biomarkers have been developed.…”

Section: Introductionmentioning

confidence: 99%

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

et al. 2013

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Invasive aspergillosis (IA) is a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and appropriate antifungal treatment is important in reducing mortality and morbidity. Despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagnosis. New rapid methods which can detect IA early in the course of disease with high sensitivity and specificity are needed to treat these infections at an early stage. Using molecular methods for the identification of Aspergillus species can be a cost-effective, rapid, discriminatory, and objective approach for delineating Aspergillus species in a clinical microbiology laboratory. PCR techniques for the diagnosis of IA have been studied for more than a decade and are still considered investigational; however, until now PCR is not included in current EORTC/MSG diagnostic criteria.

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2012

Fungal Infection

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Diagnosis of Fungal Infections

Cited by 4 publications

References 168 publications

Incontinence‐associated dermatitis: a cross‐sectional prevalence study in the Australian acute care hospital setting

Incontinence‐associated dermatitis: a cross‐sectional prevalence study in the Australian acute care hospital setting

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

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