Diagnosis of neuropathic pain in patients with osteoarthritis using questionnaires

Abstract

endoplasmic reticulum. Tenocyteblasts synthesized tropocollagen with their normal striations and arranged longitudinally to the axis of the tendon. At 8th week, S8 group exhibited fewer vessels and macrophages than S4. It can be highlighted that microkeloids areas significantly increased. PRGF8 group showed a similar state to PRGF4, although collagen fibers were more packed, with complete fiber structure and better distributed. Tenocyteblasts gradually losed their synthetic activity, transform back to tenocytes again perfectly organized and orderly with the collagen fibers. Collagen fibril diameter and priodicity showed significant differences between S and PRGF groups at any time. Conclusions: Electron microscopy of samples obtained from PRGF and S groups revealed obvious differences in the ultrastructural appearance of the tendons. S2 and S4 showed more signs of inflammation than PRGF2 and PRGF4 respectively. Microkeloid formations were observed in S groups. Fibroblast exhibited greater cellular activity and collagen production and collagen fibers were better organized and aligned in PRGF groups showing a more advanced stage of healing.