Diagnosis of oral cancer: The past and present

Reddy, G. Sridhar; Rao, K. Eswara; Kumar, Kunal; Sekhar, P. Chandra; Chandra, K Lalith Prakash; Reddy, Bale V.

doi:10.4103/0975-8844.132565

Cited by 8 publications

(4 citation statements)

References 1 publication

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“…LED-based optical sensor technology has already been shown to be suitable for the production of miniaturized chemical sensors and optical diagnostic devices (e.g., pulse oximetry and detection of oral cancer [ 43 ]). The presented combination of LEDs with simple photodiode detection provides a good alternative to full-sized spectroscopic devices and allows for a fine tuning of the analysis to the requirements of a particular practical task.…”

Section: Discussionmentioning

confidence: 99%

Development and Testing of an LED-Based Near-Infrared Sensor for Human Kidney Tumor Diagnostics

Bogomolov

Zabaryło

Kirsanov

et al. 2017

Sensors

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Optical spectroscopy is increasingly used for cancer diagnostics. Tumor detection feasibility in human kidney samples using mid- and near-infrared (NIR) spectroscopy, fluorescence spectroscopy, and Raman spectroscopy has been reported (Artyushenko et al., Spectral fiber sensors for cancer diagnostics in vitro. In Proceedings of the European Conference on Biomedical Optics, Munich, Germany, 21–25 June 2015). In the present work, a simplification of the NIR spectroscopic analysis for cancer diagnostics was studied. The conventional high-resolution NIR spectroscopic method of kidney tumor diagnostics was replaced by a compact optical sensing device constructively represented by a set of four light-emitting diodes (LEDs) at selected wavelengths and one detecting photodiode. Two sensor prototypes were tested using 14 in vitro clinical samples of 7 different patients. Statistical data evaluation using principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) confirmed the general applicability of the LED-based sensing approach to kidney tumor detection. An additional validation of the results was performed by means of sample permutation.

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Section: Discussionmentioning

confidence: 99%

Development and Testing of an LED-Based Near-Infrared Sensor for Human Kidney Tumor Diagnostics

Bogomolov

Zabaryło

Kirsanov

et al. 2017

Sensors

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“…ViziLite can effectively detect malignant lesions. More correct diagnosis of lateral spread of lesion could be possible with ViziLite than clinical examination alone [52]. However, chemiluminiscence detection method has many limitations.…”

Section: Chemiluminescencementioning

confidence: 99%

A Review on Current Scenario of Oral Cancer in India With Special Emphasis on Modern Detection Systems and Biomarkers

et al. 2020

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Oral squamous cell carcinoma is a major public health concern worldwide and a growing threat for rapidly developing economies such as India, where it ranks among the top three cancers. This review aims to discuss the national status of oral cancer in terms of incidences and mortality. We have added the emphasis on clinical characteristics of oral potentially malignant disorders and emerging optical diagnostic techniques to detect oral lesions which would otherwise go undetected by a conventional oral examination. Modern detection systems such as autofluorescence, chemiluminiscence, Narrowband imaging and Raman spectroscopy will definitely aid Conventional oral examination for diagnosis. Definitive diagnosis of oral cancer by using saliva and serum-based noninvasive biomarkers can minimize the need of tissue biopsies and patient discomfort. Urgent research efforts are required to find new ways to identify and examine high-risk population for the early diagnosis and prevention of Oral squamous cell carcinoma.

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“…It is cheaper and has low toxicity compared with toluidine blue, so can be used for oral screening on a large scale. 20,21…”

Section: Methylene Bluementioning

confidence: 99%

Conventional and Advanced Diagnostic Tools in Oral Cancer with Emphasis on Role of Dentist and Early Detection

Singla¹,

Verma²,

Goyal³

et al. 2017

Journal of Postgraduate Medicine, Education and Research

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The prevalence of oral cancer is increasing worldwide day by day. Those who suffer from oral cancer have low survival rate compared with other cancer, mainly due to delay in the diagnosis, metastases, and presence of secondary tumors. For the dental profession, it is really challenging to diagnose oral precancer or oral cancer, particularly in its early stage of the disease. Early screening and advanced diagnostic tools play an important role in the early diagnosis and treatment planning of patients suffering from oral cancer. The diagnosis method usually includes histopathology and visualization adjuncts, such as toluidine blue, vizilite, etc. This study reviews the development of new upcoming tools for early detection, emphasis on the importance of role of dentist, and early detection of oral cancer.

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Diagnosis of oral cancer: The past and present

Cited by 8 publications

References 1 publication

Development and Testing of an LED-Based Near-Infrared Sensor for Human Kidney Tumor Diagnostics

Development and Testing of an LED-Based Near-Infrared Sensor for Human Kidney Tumor Diagnostics

A Review on Current Scenario of Oral Cancer in India With Special Emphasis on Modern Detection Systems and Biomarkers

Conventional and Advanced Diagnostic Tools in Oral Cancer with Emphasis on Role of Dentist and Early Detection

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