Diagnosis of Osteoarticular - Solution is in Peripheral Blood!!

Prakash, Jyoti

doi:10.4172/1948-5948.1000271

Cited by 2 publications

(4 citation statements)

References 10 publications

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“…In the present study (Table 1) the high degree of detection was apparent in the actual clinical setting, since PCR detected 24 (46.2%) among 52 cases studied, of which culture was positive in only 13 cases (25%) and smear microscopy detected AFB in one case (1.92%). The findings of PCR in this study compare favourably with Prakash J et al 13 (40.1%) and Muangchan et al 18 (33.3%). However, differs from the study of Pandey V et al 19 (70.83%) and Negi SS et al 20 (78.2%).…”

Section: Discussionsupporting

confidence: 84%

“…Among the 20 pus swab specimens which were negative by conventional staining and culture methods, PCR detected 4 positive cases (20%) of musculoskeletal tuberculosis. The findings related to poor yield of pus was also reported in the study conducted by Ganavalli et al 14 (25.8%) and Maurya et al 21 (27.65%), However, these findings were inconsistent from the study of Ruiz et al 11 (66.67%) and Prakash et al 13 (43.24%). In the study 14 USG guided pus aspirate samples were collected from suspected musculoskeletal tuberculosis patients, among them 1 (7%) was positive on smear microscopy and 6 (42.9%) were positive on LJ culture medium, however, PCR demonstrated 10 positive (71.4%) samples.…”

Section: Discussionmentioning

confidence: 74%

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Musculoskeletal tuberculosis - A diagnostic dilemma: Clinico-bacteriological study among patients attending tertiary heath care centre in North Eastern India

2020

IJMR

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Introduction and Objectives: Clinicians consider musculoskeletal tuberculosis as diagnostic dilemma because diagnosis frequently gets delayed due to its varied clinical presentation, false negative results on smear microscopy and less sensitivity on culture methods (20-40%). The main objectives were to know the prevalence of musculoskeletal tuberculosis (TB) among patients attending NEIGRIHMS and to understand clinical bacteriological profile of musculoskeletal tuberculosis using conventional and molecular laboratory diagnostic methods. Materials and Methods:In this study, a total of fifty two clinical specimens like pus swab, ultrasonography guided (USG) pus aspiration, synovial fluid and bone biopsy of newly suspected musculoskeletal tuberculosis patients were evaluated for microscopy, culture and molecular detection of M. tuberculosis. Results:The study reveals prevalence of 46.2% musculoskeletal tuberculosis among the clinically suspected patients. The most commonly involved sites in suspected musculoskeletal tuberculosis were hip joint (23.1%). USG guided pus comprises only 26.9% of the samples collected, however, yield of M. tuberculosis from them were 71%. PCR detected the maximum number of cases of musculoskeletal tuberculosis 24 (46.2%) followed by culture method 13 (25%) and smear microscopy 1 (1.92%). Conclusion: This observation will help guiding clinicians in effective management of musculoskeletal tuberculosis cases because delayed diagnosis and treatment in musculoskeletal TB results in poor outcome.

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Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 74%

Musculoskeletal tuberculosis - A diagnostic dilemma: Clinico-bacteriological study among patients attending tertiary heath care centre in North Eastern India

2020

IJMR

View full text Add to dashboard Cite

show abstract

“…PCR in this study compare favourably with Muangchan et al18 (33.3%) and Prakash J et al13 (40.1%). However, differs from the study of Pandey V et al 19 (70.83%) and Negi SS et al 20 (78.2%).…”

supporting

confidence: 78%

mentioning

confidence: 74%