Diagnosis of Small Pancreatic Cancer by Endoscopic Balloon-Catheter Spot Pancreatography

Ikeda, Seiyo; Maeshiro, Kensei; Ryu, Shinichiro; Ogata, Kenji; Yasunami, Yohichi; Nakayama, Yoshihito; Hamada, Yusuke

doi:10.1097/mpa.0b013e31819f65c3

Cited by 15 publications

(4 citation statements)

References 36 publications

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“…Focal ductal branch dilatations and cystic lesions around the MPD were also observed (Figure 5). 56, 60, 61, 62 Recently, Kikuyama et al . reported that three out of 14 cases with PCIS had a high degree of fatty changes of the pancreatic parenchyma adjacent to PCIS, which were recognized on CT 63.…”

Section: Diagnosis Of Pcismentioning

confidence: 99%

Early diagnosis of pancreatic cancer: Current trends and concerns

Hanada

Amano

Abe

2017

Annals of Gastroent Surgery

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Early detection of pancreatic cancer (PC) is essential for a better prognosis. Some recent studies have demonstrated that a slight dilatation of the main pancreatic duct (MPD) and small cystic lesions were detected initially in most cases diagnosed at an early stage. Detecting these abnormal findings in cases with high risk factors through an effective screening system including image diagnosis, some biological markers, or familial cancer registrations should contribute to early diagnosis of PC. It has been reported that endoscopic ultrasonography (EUS) is essential for detecting tumors <10 mm with a favorable prognosis. Additionally, EUS‐guided fine‐needle aspiration biopsy is useful for confirming final histological diagnosis. For the diagnosis of stage 0 PC, local irregular stenosis of MPD should be an important initial abnormal sign detected by EUS or magnetic resonance cholangiopancreatography. Cytodiagnosis multiple times using pancreatic juice obtained by endoscopic nasopancreatic drainage should be essential for the final diagnosis. Recently, activities of regional networks between specialist doctors in medical centers and general practitioners for early diagnosis of PC have been reported in Japan. In the future, these activities may play an important role in the early diagnosis of PC.

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Section: Diagnosis Of Pcismentioning

confidence: 99%

Early diagnosis of pancreatic cancer: Current trends and concerns

Hanada

Amano

Abe

2017

Annals of Gastroent Surgery

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“…Especially for stage 0 pancreatic cancer, which is carcinoma in situ, localized main pancreatic duct stricture is often the only image finding, and detailed evaluation of the pancreatic duct image by ERP and subsequent pancreatic juice cytology are extremely important for the diagnosis. It has been reported that detailed evaluation of pancreatic duct images, including branch pancreatic ducts by endoscopic balloon catheter spot pancreatography, was useful for the diagnosis of small pancreatic cancer [84]. In addition, the usefulness of serial pancreatic juice cytology using an endoscopic nasopancreatic drainage catheter in the diagnosis of pancreatic carcinoma in situ has been reported, and the sensitivity was excellent at 72.2-100% [85][86][87].…”

Section: Diagnostic Performance Of Ercp For Pancreatic Cancermentioning

confidence: 99%

Role of Endoscopic Ultrasonography and Endoscopic Retrograde Cholangiopancreatography in the Diagnosis of Pancreatic Cancer

et al. 2021

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Pancreatic cancer has the poorest prognosis among all cancers, and early diagnosis is essential for improving the prognosis. Along with radiologic modalities, such as computed tomography (CT) and magnetic resonance imaging (MRI), endoscopic modalities play an important role in the diagnosis of pancreatic cancer. This review evaluates the roles of two of those modalities, endoscopic ultrasonography (EUS) and endoscopic retrograde cholangiopancreatography (ERCP), in the diagnosis of pancreatic cancer. EUS can detect pancreatic cancer with higher sensitivity and has excellent sensitivity for the diagnosis of small pancreatic cancer that cannot be detected by other imaging modalities. EUS may be useful for the surveillance of pancreatic cancer in high-risk individuals. Contrast-enhanced EUS and EUS elastography are also useful for differentiating solid pancreatic tumors. In addition, EUS-guided fine needle aspiration shows excellent sensitivity and specificity, even for small pancreatic cancer, and is an essential examination method for the definitive pathological diagnosis and treatment decision strategy. On the other hand, ERCP is invasive and performed less frequently for the purpose of diagnosing pancreatic cancer. However, ERCP is essential in cases that require evaluation of pancreatic duct stricture that may be early pancreatic cancer or those that require differentiation from focal autoimmune pancreatitis.

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“…The precise pancreatogram should be carried out for cases with indirect abnormal findings in PD. Endoscopic retrograde cholangiopancreatography (ERCP) and facilitating further examinations, such as cytology using pancreatic juice, has already been established for the early diagnosis of PC [6]. Recently, institutions have tended to perform magnetic resonance cholangiopancreatography (MRCP) for the diagnosis of PC due to the concern of post-ERCP pancreatitis (PEP).…”

Section: Introductionmentioning

confidence: 99%

Roles of ERCP in the Early Diagnosis of Pancreatic Cancer

et al. 2019

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It has been reported that endoscopic retrograde cholangiopancreatography (ERCP) is of value in evaluating precise pancreatograms of the pancreatic duct (PD). Recently, institutions have tended to perform magnetic resonance cholangiopancreatography (MRCP) for the diagnosis of PD due to post-ERCP pancreatitis (PEP). In small pancreatic cancer (PC), including PC in situ (PCIS) which is undetectable on cross sectional images, endoscopic ultrasonography (EUS) and MRCP serve important roles in detecting local irregular stenosis of the PD or small cystic lesions. Subsequently, ERCP and associated serial pancreatic juice aspiration cytologic examination (SPACE) obtained by endoscopic nasopancreatic drainage (ENPD) may be useful in the diagnosis of very early-stage PC. Further prospective multicenter studies are required to establish a standard method of SPACE for the early diagnosis of PC.

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Diagnosis of Small Pancreatic Cancer by Endoscopic Balloon-Catheter Spot Pancreatography

Abstract: Balloon spot pancreatography is an essential tool for the diagnosis of small ductal pancreatic cancer, and it also makes it possible to locate CIS lesions of the branch ducts.

Cited by 15 publications

References 36 publications

Early diagnosis of pancreatic cancer: Current trends and concerns

Early diagnosis of pancreatic cancer: Current trends and concerns

Role of Endoscopic Ultrasonography and Endoscopic Retrograde Cholangiopancreatography in the Diagnosis of Pancreatic Cancer

Roles of ERCP in the Early Diagnosis of Pancreatic Cancer

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