Diagnosis of Thymolipoma with Fine Needle Aspiration Biopsy

Romero-Guadarrama, Mónica Belinda; Durán-Padilla, Marco A; Cruz-Ortíz, Humberto; Castro-Gómez, Lisset; López-Vancell, Dolores; Novelo-Retana, Virginia; Santiago-Prieto, Ana Cecilia; Fierro-Chávez, Erika; Rodríguez-Martínez, Héctor A.

doi:10.1159/000326401

Cited by 12 publications

(17 citation statements)

References 11 publications

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“…An extensive literature search yielded only two cytological reports of thymolipoma, one of which was misdiagnosed as liposarcoma on FNA. 5,6 In our patient, a pre-operative FNA showed a population of mature lymphocytes together with a few epithelial cells, suggestive of thymic tissue. Although adipose tissue was not seen in the smears, a correlation with the radiological features suggested a diagnosis of thymolipoma and ruled out a possibility of teratoma.…”

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confidence: 54%

Thymolipoma in child: a case diagnosed by correlation of ultrasound‐guided fine needle aspiration (EUS‐FNA) cytology and computed tomography with histological confirmation

et al. 2013

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confidence: 54%

Thymolipoma in child: a case diagnosed by correlation of ultrasound‐guided fine needle aspiration (EUS‐FNA) cytology and computed tomography with histological confirmation

et al. 2013

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“…No siempre es fácil discernir entre un timolipoma y otras lesiones mediastínicas que contienen grasa, como un liposarcoma bien diferenciado. Romero Guadarrama et al 3 presentaron un caso de resultado falso positivo de la FNAB en un paciente con un diagnóstico erróneo de liposarcoma bien diferenciado. Por otro lado, Gupta et al 4 han publicado recientemente un caso de un niño diagnosticado mediante citología por FNA bajo guía ecográfica (EUS-FNA).…”

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Timolipoma gigante: presentación de un caso de tumor mediastínico inusual

Carillo

Fontan

Carretero

2014

Archivos de Bronconeumología

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“…Thymolipoma is another benign, slow growing neoplasm of the mediastinum. Microscopic examination may reveal thymic epithelium and/or multi-laminated keratinized cells arranged around clusters of degenerating lymphocytes (Hassall's corpuscles) [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Successful removal of a giant intrathoracic lipoma: a case report and review of the literature

et al. 2008

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We report a case of a 44-year old female who presented to her physician complaining of mild dyspnea. A follow-up chest X-ray and chest computed tomography scan revealed a giant bilateral intrathoracic mass, filling the right thoracic cavity and extending across the anterior mediastinum into the left chest cavity. This large mass caused a marked shift in the midline structures, displacing the heart to the left hemi-thorax. The patient underwent surgical removal of the thoracic and breast mass, with histologic examination confirming the diagnosis of a giant intrathoracic lipoma, weighing 4,320 grams and measured 34 × 28 × 11 cm. It is the largest intrathoracic lipoma documented in the modern literature. Case presentationA 44-year old African American female who worked as a phlebotomist presented to her primary care physician complaining of mild shortness of breath and a 4-pillow orthopnea for many years (>10 years). She was a nonsmoker, and maintained a healthy weight of 142 pounds for her 68" height. Her past medical history was significant only for uterine fibroids, for which she had undergone a myomectomy. She had conceived six healthy children, and the remainder of her family had no health problems. A subsequent chest x-ray and CT scan revealed a large mediastinal mass which occupied the majority of the right thoracic cavity and further extended across the anterior mediastinum into the left thoracic cavity ( figure 1A). The posteroinferior portion of the mass revealed several areas of dystrophic ring-type calcifications within a field of scattered dense soft tissue elements. These were thought to possibly represent a pleural-based liposarcoma, lipoma, teratoma, teratocarcinoma, or invasive thymoma of the anterior mediastinum. The mass shifted the heart and mediastinal vascular structures to the left of midline.In order to remove this large intrathoracic mass, the patient was explored through a transverse sternothoracotomy (clam-shell incision) to allow complete access to both pleural spaces and the mediastinum. Upon exposure of the anterior mediastinum, a large mass was visualized crossing this area and extending into both thoracic cavities ( figure 1B). The mass further extended into the left thoracic cavity and displaced the lower lobe of the left lung. The gross appearance was that of a thinly encapsu-

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Diagnosis of Thymolipoma with Fine Needle Aspiration Biopsy

Cited by 12 publications

References 11 publications

Thymolipoma in child: a case diagnosed by correlation of ultrasound‐guided fine needle aspiration (EUS‐FNA) cytology and computed tomography with histological confirmation

Thymolipoma in child: a case diagnosed by correlation of ultrasound‐guided fine needle aspiration (EUS‐FNA) cytology and computed tomography with histological confirmation

Timolipoma gigante: presentación de un caso de tumor mediastínico inusual

Successful removal of a giant intrathoracic lipoma: a case report and review of the literature

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