Diagnosis of Tracheopathia Osteochondroplastica

Pérez-Rodríguez, Esteban; Núñez, Nadia Acosta; Alvarado, Carlos S.; Golpe, Antonio; Casanova, Ciro; Zapatero, J.; Fogué, L.

doi:10.1378/chest.97.3.763a

Cited by 10 publications

(4 citation statements)

References 4 publications

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“…Bronchoscopy is the gold standard for TO diagnosis [6,7]. The incidence rate of TO diagnosis during autopsy is 1/6000~48/6000, and the incidence rate using bronchoscopy is 2.5/1000~3/1000 [8][9][10][11]. A large cohort study in China divided TO into three stages based on bronchoscopy and histopathology.…”

Section: Discussionmentioning

confidence: 99%

A case report of tracheobronchopathia osteochondroplastica

Wang

2023

J Clin Images Med Case Rep

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Section: Discussionmentioning

confidence: 99%

A case report of tracheobronchopathia osteochondroplastica

Wang

2023

J Clin Images Med Case Rep

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“…The prevalence of TO has been reported to be 0.01% to 4.2% in patients undergoing bronchoscopy (Table 1) [2][3][4][5][6]. TO is found at similar rates in men and women, and generally diagnosed at ≥50 years of age [7]; however, young adults and children may also be affected [8].…”

Section: Discussionmentioning

confidence: 99%

Tracheobronchopathia osteochondroplastica discovered during tracheal intubation for general anesthesia

et al. 2018

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Tracheobonchopathia osteochondroplastica (TO) is a rare disorder, where there is benign dysplasia of the trachea and occasionally large bronchi. We report the case of a 55-year-old woman who was discovered to have TO at the time of a difficult intubation. This case was also unusual because the patient had presented no previous symptoms despite the presence of extensive endotracheal lesions. The final diagnosis of TO was made after subsequent bronchoscopy in the post-operative period.

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“…When appearances are typical, biopsy is generally thought not to be essential for diagnosis [10,16], although this is refuted by one group who feel histological confirmation is necessary [18]. Histology, when available, reveals cartilaginous elements within the submucosa [10,16].…”

Section: Discussionmentioning

confidence: 99%

Airway abnormalities at flexible bronchoscopy in patients with chronic cough

Decalmer¹,

Woodcock²,

Greaves³

et al. 2007

Eur Respir J

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The algorithms utilised in the diagnosis of chronic cough advocate sequential investigations and treatment trials for asthma-like syndromes, post-nasal drip and gastrooesophageal reflux disease; however, the role of bronchoscopy is unclear. In the present authors' specialist clinic (North West Lung Centre Cough Clinic, Manchester, UK), flexible bronchoscopy is included in the diagnostic work-up of patients with chronic unexplained cough. In a retrospective review, the authors report on their experiences.Over an 18-month period, patients followed a diagnostic algorithm that included: chest radiography; pulmonary function; methacholine challenge; ear, nose and throat examination; and empirical reflux treatment. Where diagnosis remained elusive, bronchoscopy was performed.A total of 82 bronchoscopies were carried out for the sole indication of chronic cough. Patient age (mean¡SD) was 54.9¡11.22 yrs, with a median (range) cough duration of 5 (0.5-30) yrs. In nine (11%) subjects, a diagnosis was made on inspection or biopsy. These included seven cases of tracheobronchopathia osteochondroplastica (TPO), one case of elongated uvula and one case of endobronchial amyloidosis. All TPO patients had early changes, with a typical nodular appearance to the tracheal cartilage, without significant airway obstruction. These subtle changes could not have been predicted from less invasive procedures and would have been missed without bronchoscopy.Flexible bronchoscopy is indicated in persistent unexplained cough and may reveal contributing pathology.

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Diagnosis of Tracheopathia Osteochondroplastica

Cited by 10 publications

References 4 publications

A case report of tracheobronchopathia osteochondroplastica

A case report of tracheobronchopathia osteochondroplastica

Tracheobronchopathia osteochondroplastica discovered during tracheal intubation for general anesthesia

Airway abnormalities at flexible bronchoscopy in patients with chronic cough

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