Diagnostic Accuracy in Fine-Needle Aspiration of Soft Tissue and Bone Lesions: Influence of Clinical History and Experience

Abstract

A b s t r a c t Interpretation of soft tissue and bone lesions with fine-needle aspiration (

Concordance of histopathologic and cytologic grading in musculoskeletal sarcomas

“…Most important, a needle biopsy should be used to establish the presence of malignancy and to determine whether a lesion is mesenchymal. From our data and that published within the literature, [3][4][5][6][7][8][9][10][11][12] FNA appears to perform many of the same functions as core needle biopsy.…”

“…[3][4][5][6][7][8][9][10][11] Some of these studies have addressed the accuracy of FNA in histologic subtyping of mesenchymal tumors. [3][4][5][6][7][8][9][10][11] The success of subtyping tumors of the musculoskeletal system has varied among studies but generally has been between 50% and 70% accurate. 6 -10, 12 Some authors have demonstrated greater accuracy of subclassification for bone neoplasms, 12 whereas others have shown significantly less success with subclassification of soft tissue neoplasms.…”

“…4 Needle aspiration cytology is more successful at separating benign from malignant musculoskeletal lesions with diagnostic accuracy ranging between 80% and 95%. [3][4][5][6][7][8][9][10][11][12] This rate of diagnostic accuracy compares favorably with that achievable by cutting needle biopsy. 13 In the study by Mankin et al, 13 major diagnostic errors were found in up to 18.2% of surgical biopsies of musculoskeletal lesions.…”

Fine Needle Aspiration for Clinical Triage of Extremity Soft Tissue Masses

“…Close interdisciplinary collaboration and constant vigilance by the surgeon can help prevent adverse patient outcomes attributable to incorrect FNAC. It was suggested that for cytopathologists of all levels of experience, knowledge of the patients' clinical background increased the proportion of correct diagnoses and accuracy of classification [17].…”

“…Successful FNAC is contingent on two main factors: an experienced cytopathologist and close collaboration between the orthopaedic oncologist and the pathologist [11,17]. For the past 8 years we have had such a situation, allowing for collection of a large database.…”