2022
DOI: 10.3390/cancers14051351
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Diagnostic Accuracy of Contrast-Enhanced, Spectral Mammography (CESM) and 3T Magnetic Resonance Compared to Full-Field Digital Mammography plus Ultrasound in Breast Lesions: Results of a (Pilot) Open-Label, Single-Centre Prospective Study

Abstract: Introduction: To assess the diagnostic accuracy of CESM and 3T MRI compared to full-field digital mammography (FFDM), plus US, in the evaluation of advanced breast lesions. Materials and Methods: Consenting women with suspicious findings underwent FFDM, US, CESM and 3T MRI. Breast lesions were histologically assessed, with histology being the gold standard. Two experienced breast radiologists, blinded to cancer status, read the images. Diagnostic accuracy of (1) CESM as an adjunct to FFDM and US, and (2) 3T MR… Show more

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“…Of the remaining 44 eligible papers, 29 were excluded based on study quality assessment. Finally, 15 papers were deemed eligible for review [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] (Figure 1). The selection criteria for the papers included: perspective or retrospective studies, women diagnosed with breast cancer, comparison of Contrast-enhanced Spectral Mammography (CESM) and Magnetic Resonance Imaging (MRI), sensitivity and specificity metrics provided,focus on initial diagnosis.…”
Section: Methodsmentioning
confidence: 99%
“…Of the remaining 44 eligible papers, 29 were excluded based on study quality assessment. Finally, 15 papers were deemed eligible for review [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] (Figure 1). The selection criteria for the papers included: perspective or retrospective studies, women diagnosed with breast cancer, comparison of Contrast-enhanced Spectral Mammography (CESM) and Magnetic Resonance Imaging (MRI), sensitivity and specificity metrics provided,focus on initial diagnosis.…”
Section: Methodsmentioning
confidence: 99%