Diagnostic accuracy of dual-energy CT in gout: a systematic review and meta-analysis

Yu, Zhange; Mao, Tianli; Xu, Yaping; Li, Tengqi; Wang, Yanhua; Gao, Fuqiang; Sun, Wei

doi:10.1007/s00256-018-2948-y

Cited by 50 publications

(27 citation statements)

References 24 publications

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“…Eine kürzlich durchgeführte systematische Übersicht und Metaanalyse über die Verwendung von DECT zur Gicht-Diagnose zeigte eine hohe Sensitivität von 88 % und eine Spezifität von 90 % [37]. Dabei hat die DECT zwar eine hohe diagnostische Genauigkeit bei klinisch etablierter Gicht, aber eine geringe diagnostische Sensitivität bei Probanden mit erst kürzlich aufgetretener Gicht.…”

Section: Dual-energie-ct (Dect) Bei Arthritis Uricaunclassified

Computertomografie in der Rheumatologie – Update 2020

Kleyer¹,

Bayat²,

Simón³

2020

Arthritis und Rheuma

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ZUSAMMENFASSUNGDie Computertomografie (CT) ist ein dreidimensionales Bildgebungsverfahren, das sich besonders für die Darstellung des Knochens eignet. Auf Grund der häufigen knöchernen Beteiligung bei rheumatischen und muskuloskelettalen Erkrankungen ist der Einsatz für die klinische Versorgung und Forschung sinnvoll. Diese Übersichtsarbeit beschreibt den klinischen Stellenwert der hochauflösenden peripheren quantitativen Computertomografie (HR-pQCT), der Low-dose-CT sowie der Dual-Energie-CT (DECT) hinsichtlich der Diagnostik und Prognose verschiedener rheumatologischer Erkrankungen (rheumatoide Arthritis, Spondylarthropathien und Arthritis urica). Darüber hinaus wird sich auf die Bedeutung dieser bildgebenden Instrumente für die klinische Forschung fokussiert.

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Section: Dual-energie-ct (Dect) Bei Arthritis Uricaunclassified

Computertomografie in der Rheumatologie – Update 2020

Kleyer¹,

Bayat²,

Simón³

2020

Arthritis und Rheuma

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“…44,45 DECT was widely validated for the diagnosis of gout and the detection of MSU crystals. 37,44,46,47 A meta-analysis by Yu et al 48 in 2018 noted a lowest sensitivity of 75% (95% confidence interval [CI], 68-82%) and an average specificity of 93% (95% CI, 80-98%). DECT can be used to monitor the response to clinical treatment by volumetric quantification.…”

Section: Tip 4: Monosodium Urate Crystal Detection and Quantificationmentioning

confidence: 99%

“…42 This may also lead to identification of individuals with hyperuricemia, associated with increased renal, cerebrovascular, and cardiovascular risk as well as metabolic syndrome. 42,43,48…”

Section: Tip 4: Monosodium Urate Crystal Detection and Quantificationmentioning

confidence: 99%

Top-Ten Tips for Dual-Energy CT in MSK Radiology

Walstra

Hickle

Duggan

et al. 2019

Semin Musculoskelet Radiol

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Dual-energy computed tomography (DECT) has the potential to detect musculoskeletal pathology with greater sensitivity than conventional CT alone at no additional radiation dose to the patient. It therefore has the potential to reduce the need for further diagnostic imaging or procedures (e.g., joint aspirations in the case of gout or magnetic resonance imaging to confirm undisplaced fractures).DECT is a well-established technique for the detection of gout arthropathy. Multiple newer applications have shown clinical potential including bone marrow edema detection and metal artifact reduction. Collagen analysis, bone marrow lesion detection, and iodine mapping in CT arthrography are areas of possible future application and development.This article outlines 10 tips on the use of DECT imaging of the musculoskeletal system, explaining the technique and indications with practical suggestions to help guide the radiologist.

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“…11 This technology was initially used clinically to examine the composition of renal stones, but its use has been expanded to assess gout, with a diagnostic sensitivity and specificity of 88 and 90%, respectively, compared with aspiration or biopsy based on recent meta-analysis. 12…”

Section: Intratendinous Goutmentioning

confidence: 99%

Diagnostic Imaging and Management of Common Intra-articular and Peri-articular Soft Tissue Tumors and Tumorlike Conditions of the Knee

et al. 2018

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Intra-articular (IA) and peri-articular (PA) tumors of the knee are frequently encountered by orthopaedic surgeons. Nonetheless, due to the possibility of great morbidity and potential mortality, it is important to recognize and differentiate between benign and malignant lesions in a timely manner. Therefore, the purpose of this article is to provide a concise, practical, and updated review of commonly encountered IA and PA tumors including intratendinous gout, synovial chondromatosis, schwannoma, pigmented villonodular synovitis, and synovial sarcoma, and a detailed description of differentiating features to include various imaging modalities.

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Diagnostic accuracy of dual-energy CT in gout: a systematic review and meta-analysis

Abstract: DECT showed relatively high sensitivity and specificity in the diagnosis of gout. Synthetically considering these DECT abnormalities could improve the diagnostic sensitivity. More rigorous and standardized studies are still needed to support these findings.

Cited by 50 publications

References 24 publications

Computertomografie in der Rheumatologie – Update 2020

Computertomografie in der Rheumatologie – Update 2020

Top-Ten Tips for Dual-Energy CT in MSK Radiology

Diagnostic Imaging and Management of Common Intra-articular and Peri-articular Soft Tissue Tumors and Tumorlike Conditions of the Knee

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