Diagnostic accuracy of echocardiography combined with chest CT in pulmonary hypertension

Shujaat, Adil; Bajwa, Abubakr; Al‐Saffar, Farah; Bellardini, Jason; Jones, Lisa; Cury, James

doi:10.1111/crj.12610

Cited by 9 publications

(13 citation statements)

References 13 publications

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“…Davarpanah et al found PAH diameter estimate (sensitivity, 88%; specificity, 78%) in the diagnosis of PAH in comparison to echo. While Shujaat et al found that sensitivity of CT in diagnosis of PAH was (75%) and specificity was (69.57%) but they compared results of CT by right heart catheter angiography (RHC) 20 .…”

Section: Our Study Revealedmentioning

confidence: 99%

Role of Multi-Detector Computed Tomography in Assessment of Pulmonary Arterial Hypertension

Essam

Kamal²,

Osman

2018

Egyptian Journal of Hospital Medicine

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Pulmonary arterial hypertension (PAH) may be suspected based on the clinical history, physical examination and electrocardiogram findings but imaging is usually central to confirming the diagnosis, establishing a cause and guiding therapy. The diagnostic pathway of PAH involves a variety of complimentary investigations of which computed tomography pulmonary angiography (CTPA) has established a central role both in helping identify an underlying cause for PAH and assessing resulting functional compromise. In particular, CTPA is considered as the gold standard technique for the diagnosis of thromboembolic disease. This article reviews the CTPA evaluation in PAH, describing CTPA techniques, a systematic approach to interpretation and spectrum of key imaging findings.

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Section: Our Study Revealedmentioning

confidence: 99%

Role of Multi-Detector Computed Tomography in Assessment of Pulmonary Arterial Hypertension

Essam

Kamal²,

Osman

2018

Egyptian Journal of Hospital Medicine

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“…A total of 27 articles involving 4386 subjects met our inclusion criteria (table 1). 10–13 23–45 Habash’s study was divided into two independent parts because of the differences between the case group (Habash-1) and the control group (Habash-2) 27…”

Section: Resultsmentioning

confidence: 99%

“…Of the 27 eligible studies, 14 (52%) were published between 2010 to 2019,10–13 26 27 30 33 34 39 41 43–45 and 13 (48%) were published before 2010 23–25 28 29 31 32 35–38 40 42. Twelve (44%) studies were performed in Europe,12 24 26 32–35 37–39 43 44 nine (30%) in the USA,10 13 23 25 27 28 31 40 42 two (8%) in East Asia,29 36 three (12%) in the Middle East11 41 45 and one (4%) in Australia 30. Most of the studies (15/27, 56%)11 12 23 24 28–32 35 36 38 39 41 45were of prospective design versus 44% (12/27)10 13 25–27 33 34 37 40 42–44 retrospective.…”

Section: Resultsmentioning

confidence: 99%

“…All included studies used the tricuspid maximal regurgitation velocity (TRVmax) to estimate SPAP; the majority of these studies (23/27, 85%) used the classical method to calculate SPAP: 4TRVmax 2 +right atrial pressure (RAP) 10 11 13 23–28 31–37 39–45. The RAP was calculated through the diameter and collapse rate of the inferior vena cava (IVC) during spontaneous respiration in 16 (59%) studies,10 23 25–27 31 33 35–37 39–42 44 45 through the jugular vein pressure in one study (4%),24 and using a fixed value (5 or 10 mm Hg) in three studies (11%) 28 32 34.…”

Section: Resultsmentioning

confidence: 99%

“…The other included a relatively large number of studies, but did not assess a detailed subgroup analysis 7. In recent years, TTE has still been used in the clinical diagnosis of PH, and many new original studies have been published 10–13. Therefore, the purpose of our study was to undertake a comprehensive systematic review and quantitative meta-analysis on the accuracy of TTE in the diagnosis of PH.…”

Section: Introductionmentioning

confidence: 99%

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Diagnostic accuracy of transthoracic echocardiography for pulmonary hypertension: a systematic review and meta-analysis

Yan

Liu

et al. 2019

BMJ Open

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ObjectiveTo evaluate the diagnostic accuracy of transthoracic echocardiography (TTE) in patients with pulmonary hypertension (PH).DesignSystematic review and meta-analysis.Data sources and eligibility criteriaEmbase, Cochrane Library for clinical trials, PubMed and Web of Science were used to search studies from inception to 19 June, 2019. Studies using both TTE and right heart catheterisation (RHC) to diagnose PH were included.Main resultsA total of 27 studies involving 4386 subjects were considered as eligible for analysis. TTE had a pooled sensitivity of 85%, a pooled specificity of 74%, a pooled positive likelihood ratio of 3.2, a pooled negative likelihood ratio of 0.20, a pooled diagnostic OR of 16 and finally an area under the summary receiver operating characteristic curve of 0.88. The subgroup with the shortest time interval between TTE and RHC had the best diagnostic effect, with sensitivity, specificity and area under the curve (AUC) of 88%, 90% and 0.94, respectively. TTE had lower sensitivity (81%), specificity (61%) and AUC (0.73) in the subgroup of patients with definite lung diseases. Subgroup analysis also showed that different thresholds of TTE resulted in a different diagnostic performance in the diagnosis of PH.ConclusionTTE has a clinical value in diagnosing PH, although it cannot yet replace RHC considered as the gold standard. The accuracy of TTE may be improved by shortening the time interval between TTE and RHC and by developing an appropriate threshold. TTE may not be suitable to assess pulmonary arterial pressure in patients with pulmonary diseases.PROSPERO registration numberPROSPERO CRD42019123289.

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Novel Noninvasive Index Combining Echocardiography and Computed Tomography for Screening for Pulmonary Hypertension in Patients With Systemic Sclerosis

Orihara,

Min,

Eguchi

et al. 2024

CJC Open

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Diagnostic accuracy of echocardiography combined with chest CT in pulmonary hypertension

Abstract: The combination of TTE and chest CT is better than either imaging technique alone in identifying patients with PH in a heterogeneous population and may exclude PH.

Cited by 9 publications

References 13 publications

Role of Multi-Detector Computed Tomography in Assessment of Pulmonary Arterial Hypertension

Role of Multi-Detector Computed Tomography in Assessment of Pulmonary Arterial Hypertension

Diagnostic accuracy of transthoracic echocardiography for pulmonary hypertension: a systematic review and meta-analysis

Novel Noninvasive Index Combining Echocardiography and Computed Tomography for Screening for Pulmonary Hypertension in Patients With Systemic Sclerosis

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