Diagnostic accuracy of high-resolution attenuation-corrected Anger-camera SPECT in the detection of coronary artery disease

Abstract

New Anger technology incorporating innovative improvements results in high image quality with excellent interpretive certainty and high diagnostic accuracy.

Noninvasive Imaging for the Assessment of Coronary Artery Disease

“…The switch from the standard, filtered back projection reconstruction method to iterative algorithms, which include depth independent resolution recovery, noise regularization, and scatter and attenuation correction, has improved the signalto-noise ratio and image quality. This also allows for low-dose imaging using a standard acquisition time with reduced radiation exposure to the patient and operator,without compromising image quality and accuracy in the detection of CAD [30][31][32]. This is consistent with the American Society of Nuclear Cardiology's goal to reduce the radiation dose to ≤9 mSv in 50% of MPI studies by 2014.…”

Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging Guidelines: Instrumentation, Acquisition, Processing, and Interpretation

“…However, recent studies have demonstrated the potential superiority of 128 matrix with 3.2-mm pixel size when new reconstruction methods with resolution recovery are used on standard SPECT cameras. 55 For the CZT SPECT camera systems, the usual pixel size is 2.5 mm and 128 x 128 matrix size.…”

Failure to accurately identify the number of diseased coronary arteries: A weakness of SPECT MPI

“…4 Improvements in detection of left main disease have been demonstrated with attenuation corrected SPECT 5 and improvements in detection of multivessel CAD have recently been demonstrated using a high-resolution SPECT camera incorporating linesource attenuation correction, noise reduction, and resolution recovery algorithms. 6 Use of a newer generation CZT SPECT camera has also been shown to result in improved accuracy for detecting multi-vessel CAD. 7 …”