Diagnostic accuracy of salivary cortisol as a marker of premenstrual syndrome degrees in adolescents

Siregar, Muhammad Fidel Ganis

doi:10.11138/giog/2015.37.6.273

Cited by 1 publication

(1 citation statement)

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“…Level of morning testosterone is the highest level [ 15 ] [ 22 ], so it is often used as a basal testosterone index to get the picture of the maturation process [ 22 ]. A sampling of saliva by passive drool method gave better results than using salivettes [ 23 ] [ 24 ]. Examination of salivary testosterone with enzyme-linked immunosorbent assay (ELISA) method proved to have high sensitivity and specificity with stable results [ 15 ], but saliva samples were very sensitive to blood contamination [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

The Effect of Psychological Stress on Salivary Testosterone in Puberty Children

Prastyo¹,

Deliana²,

Dimyati³

et al. 2018

Open Access Maced J Med Sci

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BACKGROUND:Psychological stress is a condition that is experienced by many adolescents which affect the Hypothalamic-Pituitary-Gonadal axis. Testosterone is known as a sex steroid hormone that is susceptible to acute stress and can be measured through saliva. Disruption of the reproductive system can affect the sexual maturation process.AIM:To understand the difference in salivary testosterone levels in puberty children before and after given a stressor.METHODS:A quasi-experimental intervention study was conducted at Antonius Bangun Mulia junior high school, Medan, North Sumatera, in July-October 2017. Subjects were students aged 12-14 years with sexual maturity G2 for boys and M2 for girls. Psychological stress intervention was generated by the Wechsler intelligence scale for children fourth edition (WISC IV). Saliva was collected before and after the intervention. The analysis was done with Wilcoxon test and a P value < 0.05 was considered significant.RESULTS:Forty-two subjects of 24 male students and 18 female students with sexual maturation Tanner II (54.8%) and Tanner III (45.2%). This study obtained that there was a statistically significant difference in salivary testosterone levels before and after the subject was given a stressor (P = 0.015, CI 95%). This difference also was seen within sexual maturation Tanner II (P = 0.045, CI 95%). No difference was observed in testosterone levels based on gender, male students (P = 0.065, CI 95%) and female students (P = 0.112, CI 95%).CONCLUSION:Stress can affect salivary testosterone levels. There was a statistically significant difference in salivary testosterone levels before and after psychological stress in puberty children.

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