Diagnostic accuracy of transabdominal ultrasound in detecting prenatal cleft lip and palate: a systematic review

Abstract

Objectives To systematically review the diagnostic accuracy of second-trimester transabdominal ultrasound in detecting orofacial clefts in low-and high-risk populations and to compare two-dimensional (2D) with three-dimensional (3D) ultrasound techniques.Methods MEDLINE and EMBASE were searched for articles published in English, Dutch, French or German using the keywords 'cleft' and 'ultrasound' or 'screening' or 'sonogram' and 'prenatal' or 'antenatal' or 'fetus

Prenatal indices for mandibular retrognathia/micrognathia

“…Alternatively, they bildungen von Lippen, Kiefer und Gaumen kombiniert [3,15,42,43,44]. Während Spaltbildungen der Lippe und des Oberkiefers heute sonographisch bereits sehr zuverlässig festgestellt werden können [6,24,25,30,37,53,54], gelingt die Detektion von isolierten Gaumenspalten, die besonders oft mit weiteren Fehlbildungen assoziiert sein können, meist nicht [26]. Da in diesen Fällen Neugeborene häufiger schwerwiegende Ernäh-rungsprobleme und/oder eine lebensbedrohliche Ateminsuffizienz entwickeln können (z.…”

Tessier 30 Facial Cleft- Median Cleft of Upper and Lower Lip, Lower Alveolus and Mandible, Ankyloglossia and Cervical Teratoma

“…30 in Tessier's classification. This anomaly was first time reported by Couronne in 1819 [1]. So far upto 70 cases have been described in history.…”

Fetal Kraniyospinal ve Fasiyal Anomaliler

“…Yarık damak ise uvuladan başlayarak öne doğ-ru önce yumuşak damak sonra da sert dama-ğı etkileyecek şekilde ilerler [24]. İzole yarık damağın antenatal tanısı zordur [25]. Bunların %25'inin altında karyotip anormallikleri, eşlik eden başka anomaliler ya da genetik sendromlar yatar [26].…”