Diagnostic accuracy of ultrasound imaging in Hashimoto's thyroiditis

Kapali, Anuradha; Jaipal, Beerappa; Raghuram, P; Bangar, Ravindra

doi:10.4103/0973-0354.200567

Cited by 2 publications

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“…The positive and negative predictive values of USS examination for chronic autoimmune thyroiditis are 88% and 90.9%, respectively. The overall accuracy of USS in diagnosing chronic autoimmune thyroiditis is 90.1% (23). It was 74.2% in this study.…”

Section: Ultrasonographic Assessment Of Thyroid In Patients With Chronic Auto Immune Thyroiditismentioning

confidence: 47%

“…Hypoechogenicity and increased vascularity are most sensitive parameters to diagnose Hashimoto's thyroiditis where as micronodules were most specific parameter for the diagnosis. Coarsened echo texture has an intermediate sensitivity and specificity for diagnosis of Hashimoto's thyroiditis by ultrasonography (23). The USS examination is 78.5% sensitive and 95.2% specific in diagnosing chronic autoimmune thyroiditis.…”

Section: Ultrasonographic Assessment Of Thyroid In Patients With Chronic Auto Immune Thyroiditismentioning

confidence: 95%

“…Although the other similar nodules that are hyper and hypoechoic are included as micronodules yet the solitary nodules and dissimilar nodules are not classified as micronodules. Colour Doppler is used to assess thyroid vascularity (23).…”

Section: Ultrasonographic Assessment Of Thyroid In Patients With Chronic Auto Immune Thyroiditismentioning

confidence: 99%

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Chronic autoimmune thyroiditis: a challenging clinical entity in surgical practice

Rajendra¹

2019

Sri Lanka j Surg

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IntroductionChronic autoimmune thyroiditis is frequently encountered in surgical practice. However clinical data on chronic autoimmune thyroiditis has limited publications arising from Sri Lanka. This study presents our experience of this clinical entity which has differing thyroid morphologies and thyroid functional status at presentation. ObjectiveThe objective of this study was to analyse the spectrum of clinical profiles in patients with chronic auto immune thyroiditis attending at a surgical clinic. The clinical profiles analysed were the age and gender distribution, clinical presentation, thyroid functional status, thyroid peroxidase antibody (TPO Ab) status, Fine Needle Aspiration Cytology (FNAC) findings, Ultrasonographic (USS) assessment and association of thyroid malignancies. Formulation of a diagnostic guideline was also considered. Study designThis is an observational study using the clinical profiles of patients with thyroid diseases registered in the surgical clinic from January 2009 to December 2018. Patients diagnosed to have chronic auto immune thyroiditis were included in this study. Different clinical profiles of these patients were analyzed. ResultsOut of 226 patients with thyroid diseases registered to the surgical clinic over a decade, 89 (39.4%) had chronic auto immune thyroiditis confirmed by either TPO Ab or FNAC or by both. Thyroid morphology and thyroid functional states of patients with chronic auto immune thyroiditis at presentation varied widely; 57.3%, 27% and 15.7% had diffuse goitre, multinodular goitre and solitary nodule respectively and 66.3%, 28.1% and 5.6% were hypothyroid, euthyroid and hyperthyroid state respectively. An USS of thyroid gland performed on 83 patients revealed sonographic features suggestive of thyroiditis in 67 patients (75.2%). The association between USS detected chronic autoimmune thyroiditis and the presence of hypothyroid state at presentation was statistically significant (p= 0.027). Associated thyroid malignancies were detected in thyroidectomy specimens of 6 patients; 5 were papillary and one was follicular carcinoma. ConclusionThe thyroid morphology and functional status are not unique in patients with chronic autoimmune thyroiditis. There is a risk of having associated thyroid malignancy. USS evaluation of patients could be included in the guideline for diagnosis to mitigate the challenges faced in the surgical management of chronic autoimmune thyroiditis.

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Section: Ultrasonographic Assessment Of Thyroid In Patients With Chronic Auto Immune Thyroiditismentioning

confidence: 47%

Section: Ultrasonographic Assessment Of Thyroid In Patients With Chronic Auto Immune Thyroiditismentioning

confidence: 95%

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Chronic autoimmune thyroiditis: a challenging clinical entity in surgical practice

Rajendra¹

2019

Sri Lanka j Surg

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“…Diagnosis of Hashimoto's thyroiditis (chronic autoimmune thyroiditis) was determined by presence of antibodies to thyroglobulin (anti-TG) and/or thyroid peroxidase (anti-TPO) and/ or ultrasonographical features suggestive of Hashimoto's thyroiditis (enlarged gland, which is hypoechoic, with coarsened parenchyma and is often hypervascular) and/or previous patho-logic verification after a fine-needle aspiration biopsy for thyroid nodule evaluation (17). Demographic features were obtained for all cases.…”

Section: Methodsmentioning

confidence: 99%

Association Between Chronic Autoimmune Thyroiditis and Nesfatin-1 Levels

Dellal¹,

Niyazoğlu

Hatipoğlu

et al. 2022

Kocatepe Tıp Dergisi

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AMAÇ: Bu çalışmanın amacı kronik tiroiditli hastalarda nesfatin-1 düzeyi ile tiroid otoimmünitesi arasındaki ilişkiyi değerlendirmektir.GEREÇ VE YÖNTEM: Hashimoto tiroiditli 49 premenopozal kadın ve yaş ve vücut kitle indeksi (VKI) uyumlu 23 sağlıklı kadın, bu kesitsel karşılaştırmalı çalışmaya dahil edildi. Plazma nesfatin-1, açlık ve tokluk glukoz, hemoglobin A1c (HbA1c), açlık insülin, kolesterol parametreleri, serbest tiroksin (ST4), serbest T3 (ST3), tirotropin (TSH), anti-tiroid peroksidaz antikor (anti-TPO) and anti-tiroglobin (anti-TG) antikor değerleri için kan örnekleri alındı. Ek olarak tüm vakalarda, insülin direnci için homeostatik model değerlendirmesi (HOMA-İR) ve vücut kitle indeksi (VKİ) hesaplandı ve bel/kalça oranı ölçüldü.BULGULAR: Hashimoto tiroiditli hastaların ortalama yaşı 35,5±8,1, kontrol grubunun ise 33,2±7,1 idi (p=0.324). VKI ve bel/kalça oranı, gruplar arasında benzerdi (p=0.239 ve p=0.317). TSH, anti-TPO ve anti-TG düzeyleri hasta grubunda anlamlı derecede yüksekti (p=0.023, p<0.001 ve p<0.001). Hastalarda trigliserid düzeyleri istatistiksel anlamlılık sınırında daha yüksekti(p=0.05). Her iki grup arasında nesfatin düzeyleri açısından istatistiksel anlamlı farklılık yoktu [0,4 (0,39-0,43), 0,39 (0,39-0,39) ng/ml;p=0.329].SONUÇ: Kronik otoimmün tiroiditte tiroid hormon değişiklikleri ya da otoimmünite, nesfatin-1 düzeylerinde değişikliğe yol açmayabilir. Hashimoto tiroiditli hastalardaki tokluk ve enerji tüketiminden nesfatin-1 dışındaki mekanizmalar sorumlu olabilir.

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Diagnostic accuracy of ultrasound imaging in Hashimoto's thyroiditis

Cited by 2 publications

References 0 publications

Chronic autoimmune thyroiditis: a challenging clinical entity in surgical practice

Chronic autoimmune thyroiditis: a challenging clinical entity in surgical practice

Association Between Chronic Autoimmune Thyroiditis and Nesfatin-1 Levels

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