Diagnostic accuracy of upper limb neurodynamic tests for the assessment of peripheral neuropathic pain: A systematic review

Abstract

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Diagnostic accuracy of patient interview items and clinical tests for cervical radiculopathy

“…One systematic review concluded that, despite the high sensitivity, the clinical neurological examination is associated with misclassification in cervical radiculopathy, due to its poor specificity [12]. These con-tradictory results might be explained by the difference in reference standard used (needle electromyography versus clinical presentation combined with medical imaging) and patient population (patients with Grade III neck pain [28] versus patients suspected for cervical radiculopathy).…”

The effectiveness of early diagnostic tools for neural lesions in leprosy An observational cohort study

“…Leprosy patients test positive when submitted to Neurodynamic Assessment of lower limbs [23] . But, even when the tests do not reproduce the symptoms in the affected nerves, characterizing negative tests, studies suggest that a neuropathy cannot be ruled out yet, this can mean a more severe lesion with demyelination of the fibres [33] (as occurred in degree 2 patients that tested negative in the lower limbs in our analysis), producing a possible false negative result [18] , thus explaining the low sensitivity of the NDA in lower limbs, because low sensitivity produces more false negative results [18] .…”

“…They should be interpreted in the context of a loss of function tests of small fibres in a domain [32] . Combining anamnesis and clinical history is an important tool to make the differential diagnosis, where the combination of negative neurodynamic test results could be used to rule out a disorder in the peripheral nerves; with limited evidence, they are relevant in cervical radiculopathies [33] .…”

Quantifying the Elasticity Properties of the Median Nerve during the Upper Limb Neurodynamic Test 1

“…The upper limb neurodynamic test 1 (ULNT1) consists of a series of movements constructed to stress various parts of the nervous system and is regarded to be capable of detecting increased nerve mechanosensitivity [ 1 , 2 ]. Clinicians use range of motion (ROM) and sensory responses to evaluate neurodynamic tests and compare sides and/or relate results to normal values in order to diagnose upper extremity peripheral neuropathic pain [ 3 , 4 ].…”