Diagnostic and prognostic criteria of chronic left ventricular failure obtained during exercise-201Tl imaging

J, Bureau; Gaillard, J; Granier, R.; Ollivier, Jean

doi:10.1007/bf00284537

Cited by 7 publications

(5 citation statements)

References 5 publications

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“…A study by Wu et al[11] in 2003 reported that SPECT was only of modest value to distinguish between ischemic and idiopathic cardiomyopathy and concluded that SPECT cannot be relied upon in an individual patient to differentiate the two entities. Overall, the existing literature points to a high sensitivity for SPECT in CAD detection (nearly 100% in some published studies) while specificity on average is only about 40%-50% in LVD patients[12-15]. …”

Section: Discussionmentioning

confidence: 99%

Coronary artery disease detection - limitations of stress testing in left ventricular dysfunction

Bomb¹,

Kumar²,

Chockalingam³

2017

WJC

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Incidental diagnosis of left ventricular systolic dysfunction (LVD) is common in clinical practice. The prevalence of asymptomatic LVD (Ejection Fraction, EF < 50%) is 6.0% in men and 0.8% in women and is twice as common as symptomatic LVD. The timely and definitive exclusion of an ischemic etiology is central to optimizing care and reducing mortality in LVD. Advances in cardiovascular imaging provide many options for imaging of patients with left ventricular dysfunction. Clinician experience, patient endurance, imaging modality characteristics, cost and safety determine the choice of testing. In this review, we have compared the diagnostic utility of established tests - nuclear and echocardiographic stress testing with newer techniques like coronary computerized tomography and cardiac magnetic resonance imaging and highlight their inherent limitations in patients with underlying left ventricular dysfunction.

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Section: Discussionmentioning

confidence: 99%

Coronary artery disease detection - limitations of stress testing in left ventricular dysfunction

Bomb¹,

Kumar²,

Chockalingam³

2017

WJC

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“…The overlapping was quite small, resulting in good discriminative ability. The study by Bureau et al (1987) compared the initial study mean pulmonary counts/ mean myocardial counts in the brightest segment with the late study mean pulmonary counts/mean myocardial counts in the brightest segment in the initial study (! ); these results are difficult to compare with other work in the field.…”

Section: Discussionmentioning

confidence: 99%

“…Temporal changes in PM uptake ratios were considered in three studies (Kushner et al 1981 ;Lahiri et al 1984;Bureau et al 1987) with conflicting results and utilizing three different methods of assessment. Temporal changes in pulmonary T1 content were addressed in three studies (Bingham et al 1980;Kushner et al 1981;Levy et al 1983), all measuring T1 uptake in the upper left lung, without considering the possibility of variation between lung regions.…”

Section: Introductionmentioning

confidence: 99%

Spatial distribution and temporal changes of pulmonary thallium uptake in myocardial perfusion studies

Mannting

1990

Eur J Nucl Med

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Spatial distribution and temporal changes in pulmonary thallium uptake were assessed in 24 normal subjects and 35 patients with coronary artery disease (CAD). In studies carried out directly after stress and 3 h later, pulmonary Tl uptake was assessed as body surface area corrected absolute pulmonary uptake in the upper, middle and lower right lung regions, and in the total right lung and upper left lung. Pulmonary/myocardial (PM) uptake ratios for these 5 regions were calculated as mean pulmonary/mean background-corrected myocardial uptake. Additionally, wash-out was assessed for each region and for the myocardium. In normal subjects, the initial pulmonary Tl uptake, the PM ratios and Tl wash-out were greater in the lower lung regions than in the upper. In the late studies, no significant differences in Tl content or PM ratios were found among the regions. In patients with CAD, initial pulmonary Tl uptake and PM ratios were greater in the lower than in the upper regions, and higher than for the normal subjects in all pulmonary regions (P less than 0.001). Tl wash-out was significantly higher in the low and middle regions versus the upper region (P less than 0.001) and higher in all regions than in normal subjects (P less than 0.001). In the late studies no significant differences in Tl content or PM ratios were found between any pulmonary regions. Pulmonary Tl content was, in all regions, higher in CAD than in normal subjects (P less than 0.01), as were the PM ratios (P less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

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“…In a further study by Bureau et al (1987), the authors used a lung/heart ratio acquired immediately after stress, which they called the lung stress index (LSI). A similar index was used after the patient had rested for 3 h and was called the lung redistribution index (LRI).…”

Section: Increased Lung Uptake Of 2°1ti After Stress Testmentioning

confidence: 99%

“…Summary of major studies involving thallium-201 lung/ heart ratios 1980 Boucher et al 1981Kushner et al 1983Levy et al 1984Lahiri et al 1985Rothendler et al 1987Bureau et al 1987Gill et al 1988Kaul et al 1988Miller et al 1989Kahn et al 1990Mannting 1991Kurata et al 1991 Ilmer et al Summary of major studies involving thallium-201 lung/ heart ratios 1980 Boucher et al 1981Kushner et al 1983Levy et al 1984Lahiri et al 1985Rothendler et al 1987Bureau et al 1987Gill et al 1988Kaul et al 1988Miller et al 1989Kahn et al 1990Mannting 1991Kurata et al 1991 Ilmer et al…”

Section: Introductionmentioning

confidence: 99%

The use of thallium-201 lung/heart ratios

1992

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This survey gives an overview of the methodology of thallium-201 lung/heart uptake ratios often used as an independent factor in the assessment of patients with coronary artery disease undergoing myocardial perfusion scintigraphy. Different techniques have been used in the past. The most sensitive method is one which calculates a lung/heart ratio from scintigraphy obtained immediately after cessation of exercise. If single photon emission tomography (SPET) is routinely performed the anterior projection of the data set obtained during tomographic acquisition should be used in preference to a separate planar anterior static images recorded before or after the SPET procedure. The lung/heart ratio is useful as a prognostic indicator of outcome as it accurately mimics the degree of left ventricular dysfunction. With the increasing popularity of pharmacological stress testing there is evidence that this ratio still offer valid information. Additional work in this field is nevertheless required to further confirm this observation. In routine clinical practice, the lung/heart ratio should help and enable physicians to prioritise patients for urgent intervention.

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Diagnostic and prognostic criteria of chronic left ventricular failure obtained during exercise-201Tl imaging

Cited by 7 publications

References 5 publications

Coronary artery disease detection - limitations of stress testing in left ventricular dysfunction

Coronary artery disease detection - limitations of stress testing in left ventricular dysfunction

Spatial distribution and temporal changes of pulmonary thallium uptake in myocardial perfusion studies

The use of thallium-201 lung/heart ratios

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