Diagnostic Approach to Intrinsic Abnormality of Spinal Cord Signal Intensity

Lee, Michael J; Aronberg, Ryan; Manganaro, Matthew S.; Ibrahim, Mohannad; Parmar, Hemant

doi:10.1148/rg.2019190021

Cited by 32 publications

(27 citation statements)

References 58 publications

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“…The contused nerve underwent edema and initiated the micro de-arrangement that represents an abnormal signal in MRI. Although the intramedullary signal changes of the spinal cord are frequently observed in the degenerative cervical spine, the presence of acute myelopathy along with this abnormal signal may reflect edema or blood-spinal cord barrier breakdown [11] , [12] .…”

Section: Discussionmentioning

confidence: 99%

Particular precautions and the role of intraoperative neuromonitoring in cervical cord injury in elder recreational cyclist: A case report

Saleh

Librianto²,

Kamal³

et al. 2022

International Journal of Surgery Case Reports

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Section: Discussionmentioning

confidence: 99%

Particular precautions and the role of intraoperative neuromonitoring in cervical cord injury in elder recreational cyclist: A case report

Saleh

Librianto²,

Kamal³

et al. 2022

International Journal of Surgery Case Reports

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“…They commonly present with features of myelopathy with altered spinal cord signal intensity on MR images. This group encompasses multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), neuromyelitis optica spectrum disorder (NMOSD), and idiopathic transverse myelitis (TM) [2][3][4].…”

Section: Demyelinating Disordersmentioning

confidence: 99%

“…Multiple sclerosis is an immune-mediated demyelinating disease of the central nervous system which affects the brain and spinal cord. This is the most common demyelinating disease and affects females more commonly than males [3]. McDonald's criteria that assist in the diagnosis of this condition are based on demonstrating the multiplicity of the clinical attacks and the radiologic evidence of lesions being disseminated in space and time along with the presence of oligoclonal bands in CSF [5,6].…”

Section: Multiple Sclerosis (Ms)mentioning

confidence: 99%

“…In addition to the pattern of clinical presentation, analysis of certain features on MRI may help to narrow down the differential diagnosis. These features include distribution and location of the abnormal signal, the longitudinal extent of cord involvement (short segment or long segment), the cross-sectional area involved, and the enhancement pattern [3]. In addition, the multiplicity of the lesion(s), presence of cord swelling, and the specific region of the spinal cord that is involved also need to be evaluated.…”

Section: Introductionmentioning

confidence: 99%

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Radiological approach to non-compressive myelopathies

Swarup

Chandola

Batra

et al. 2022

Egypt J Radiol Nucl Med

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Background Myelopathy, a pathological condition related to the spinal cord can broadly be categorized into compressive and non-compressive aetiologies. Magnetic resonance imaging remains the modality of choice when suspecting non-compressive myelopathy as it helps to localize the affected segment and exclude compression as the cause of myelopathy. This review deals with the imaging approach for non-compressive myelopathies. Main body Demyelinating disorders are the most common cause of non-compressive myelopathy and often show confounding features. Other causes include inflammatory, ischemic, metabolic, and neoplastic disorders. Non-compressive myelopathy can broadly be classified into acute and non-acute onset which can further be categorized according to the distribution of the signal abnormalities, including length of cord involvement, specific tract involvement, enhancement pattern, and the region of the spinal cord that is affected. Conclusions Imaging plays a critical role in the evaluation of clinically suspected cases of myelopathy and MR imaging (with or without contrast) remains the preferred modality. Compressive causes must be excluded as a cause of myelopathy. Despite a multitude of causes, the most common imaging appearance is a nonspecific T2 hyperintense signal in the spinal cord, and thus, a pragmatic diagnostic approach along with appropriate clinical and biochemical correlation is essential for arriving at an accurate diagnosis.

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“…Однако наличие только повышения сигнала на Т2-взвешенных изображениях не является специфическим, так как подобные изменения наблюдаются практически при любом типе поражения спинного мозга, включая миелопатию, инфаркт спинного мозга, опухолевые поражения. В некоторых случаях, например в острейшем периоде инфаркта спинного мозга, изменения на Т2-взвешенных изображениях могут не определяться, контрастное усиление на Т1-взвешенных изображениях также не является специфическим [21]. В этих случаях для исключения инфаркта спинного мозга целесообразно использовать диффузионно-взвешенные изображения с построением карт измеряемого коэффициента диффузии, так как они являются высокочувствительными к ишемическому повреждению, даже в острейшую фазу.…”

Section: в течение 1-х суток госпитализации уровень гипестезии поднял...unclassified

Informative value of neurophysiological and neuroimaging research methods in the onset of spinal cord myelopathy: literature review and clinical observation

Kanshina

Surma

Бадамшина

et al. 2022

Neuromuscular Diseases

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Vascular myelopathy is a variant of acute or subacute lesions of the spinal cord as a result of circulatory disorders in the local vascular basin or hemodynamic changes in the vessels of distant localization.A clinical case of a patient with vascular myelopathy at the thoracic level is presented, the anamnesis of the disease, the results of examination and instrumental research methods with an assessment of the significance of diagnostic transcranial magnetic stimulation at the onset of the disease are presented.The purpose of this publication is to demonstrate the informative value of diagnostic transcranial magnetic stimulation and magnetic resonance imaging in the onset of vascular myelopathy of the spinal cord.A clinical case of a patient with vascular myelopathy at the thoracic level is presented, the history of the disease, the results of examination and instrumental methods of investigation are considered, with an assessment of the significance of diagnostic transcranial magnetic stimulation in the onset of the disease. A review of the literature was carried out in order to assess the information content of neurophysiological and neuroimaging studies in vascular myelopathy. In patients with onset of spinal cord infarction, the study of motor evoked potentials can demonstrate the involvement of cortico-spinal projections even in the absence of neuroimaging data of their damage during 48 hours.The transcranial magnetic stimulation with the analysis of motor evoked potentials is a reliable tool for diagnosing damage to cortico-spinal projections in the onset of vascular myelopathy.

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Diagnostic Approach to Intrinsic Abnormality of Spinal Cord Signal Intensity

Cited by 32 publications

References 58 publications

Particular precautions and the role of intraoperative neuromonitoring in cervical cord injury in elder recreational cyclist: A case report

Particular precautions and the role of intraoperative neuromonitoring in cervical cord injury in elder recreational cyclist: A case report

Radiological approach to non-compressive myelopathies

Informative value of neurophysiological and neuroimaging research methods in the onset of spinal cord myelopathy: literature review and clinical observation

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