2021
DOI: 10.1186/s13256-021-03080-1
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Diagnostic challenge and surgical management of Boerhaave’s syndrome: a case series 

Abstract: Background Boerhaave’s syndrome is the spontaneous rupture of the esophagus, which requires early diagnosis and treatment. Symptoms may vary, and diagnosis can be challenging. Case presentation Case 1: A 54-year-old Chinese man presented to us with sudden-onset epigastric pain radiating to the back following hematemesis. Upper gastrointestinal endoscopy revealed a full-thickness rupture of the esophageal wall. Subsequent computed tomography showed … Show more

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Cited by 4 publications
(5 citation statements)
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“…Although many cases of spontaneous esophageal rupture have been reported, the lack of specific symptoms of this condition continues to pose a challenge[ 7 ]. Mackler's triad comprising an acute presentation of retching or vomiting, lower chest pain, and surgical emphysema, is a clinical manifestation with relatively high specificity for the diagnosis of spontaneous esophageal rupture.…”
Section: Discussionmentioning
confidence: 99%
“…Although many cases of spontaneous esophageal rupture have been reported, the lack of specific symptoms of this condition continues to pose a challenge[ 7 ]. Mackler's triad comprising an acute presentation of retching or vomiting, lower chest pain, and surgical emphysema, is a clinical manifestation with relatively high specificity for the diagnosis of spontaneous esophageal rupture.…”
Section: Discussionmentioning
confidence: 99%
“…Chest pain and subcutaneous emphysema are also found in Boerhaave's syndrome, which consists of esophageal rupture due to increased intraesophageal pressure, and lack of cricopharyngeal sphincter relaxation [12]. However, unlike spontaneous pneumomediastinum, in Boerhaave's syndrome these findings are usually accompanied by a history of vomiting (Mackler triad).…”
Section: Esophageal Perforation (Boerhaave's Syndrome)mentioning
confidence: 99%
“…Dyspnea, cough, sore throat, dysphonia, dysphagia, palpitations, and neck pain may be present [13]. It is a rare and dangerous condition due to the extravasation of gastric contents into the mediastinum and pleura, leading to infection and death [12,14]. Chest X-ray findings include interposition of air between the heart and the diaphragm, thymus elevation by air, and subcutaneous emphysema [13,14].…”
Section: Esophageal Perforation (Boerhaave's Syndrome)mentioning
confidence: 99%
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