Diagnostic Challenge to Distinguish Gastric Duplication Cyst from Pancreatic Cystic Lesions in Adult

Abstract

We report herein a 63-year-old

Gastric Duplication Cyst: Two Case Reports and Review of the Literature

“…Because most cases occur along the greater curvature of the stomach, the cysts can potentially compress the adjacent organs such as pancreas, kidney, spleen, and adrenal gland. Accordingly, the differential diagnosis would include lesions arising from these organs [2]. The cysts may also be manifested by complications such as infection, gastrointestinal bleeding, perforation, ulceration, fistula formation, obstruction, compression, or carcinoma arising in the cysts [7, 8].…”

“…Classically, radiographic studies show an intramural filling defect indenting the gastric contour [8]. Contrast-enhanced CT scan typically demonstrates GDC as a thick-walled cystic lesion with enhancement of the inner lining [2]. Calcification is occasionally observed on CT.…”

“…Calcification is occasionally observed on CT. These findings are of diagnostic significance for GDCs [2]. However, since mucinous cystic tumors of the pancreas also show similar radiological features, GDCs adjoining the pancreas are indistinguishable from pancreatic mucinous cystic tumors based on these CT findings.…”

“…However, the nature of the fluid in the GDC was reported to differ in each case according to bleeding, chronic inflammation, or infection. Therefore, MRI seems to be of less significance than expected in diagnosing GDCs [2]. EUS is useful in distinguishing between the intramural and extramural lesions of the stomach.…”

“…It can affect any part of the gastrointestinal tract with ileum being the most common site [1, 2]. These malformations are believed to be congenital, formed before the differentiation of epithelial lining, and therefore named for the organ with which they are associated [3].…”