Diagnostic Criteria for Chronic Pancreatitis by the Japan Pancreas Society

Homma, Tatsuji; Harada, Hideo; Koizumi, Masaru

doi:10.1097/00006676-199707000-00002

Cited by 125 publications

(70 citation statements)

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“…Therefore, although the criteria could diagnose relatively advanced cases as definite or probable CP (Homma et al 1997;Otsuki 2003), the criteria could not diagnose early cases (Otsuki 2004). To improve the prognosis of patients with CP, early diagnosis is necessary because advanced CP is progressive and irreversible (Chari and Singer 1994) and the average age of death is significantly young, especially in patients with alcoholic CP (Otsuki 2003;Ammann 2006).…”

Section: Discussionmentioning

confidence: 99%

Distinct Clinical Features of Two Patients That Progressed from the Early Phase of Chronic Pancreatitis to the Advanced Phase

Hirota

Shimosegawa

Kanno

et al. 2012

Tohoku J. Exp. Med.

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Chronic pancreatitis (CP) has been considered an intractable inflammatory disease that is progressive and irreversible after definite structural changes appear in the pancreas. The Japanese diagnostic criteria for CP were revised in 2009. One of the reasons for this revision was to define a diagnostic criterion for the early phase of CP (early CP) to improve a patient's clinical outcome, because the disease progression might be reversed in this phase by a therapeutic intervention. However, the clinical features and outcome of early CP remain largely unknown, and the diagnostic reliability of early CP needs to be verified. Here, we show two patients who met the diagnostic criteria of early CP and then progressed to the advanced, late phase of CP (definite CP). A 64-year-old man with recurrent acute pancreatitis was diagnosed as early CP and later progressed to definite CP with multiple pancreatic calcifications at the age of 69. The etiology of CP in this patient was thought to be idiopathic. The other patient was a 57-year-old man with alcohol abuse (ethanol consumption > 120 g/day). He was diagnosed as early CP and then rapidly progressed to definite CP without any acute attack. He could not remain abstinent after the diagnosis of early CP. In the present report, we retrospectively demonstrated distinct clinical features of the two patients, both of whom were diagnosed as early CP first and then progressed to definite CP. Thus, our findings support the disease concept of early CP and also suggest the validity of the revised Japanese criteria for the diagnosis of early CP.

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Section: Discussionmentioning

confidence: 99%

Distinct Clinical Features of Two Patients That Progressed from the Early Phase of Chronic Pancreatitis to the Advanced Phase

Hirota

Shimosegawa

Kanno

et al. 2012

Tohoku J. Exp. Med.

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“…The diagnostic criteria for chronic pancreatitis currently used in Japan were proposed by the Japan Pancreas Society (JPS) in 1995 (JPS Criteria 1995) [10,11]. The JPS Criteria 1995, which can be applied primarily to patients presenting with symptoms and findings suggestive of chronic pancreatitis, classify chronic pancreatitis into (i) definite; (ii) probable, and (iii) possible chronic pancreatitis, excluding obstructive, inflammatory (autoimmune) and tumor-forming pancreatitis from the definition of chronic pancreatitis.…”

Section: Diagnostic Criteria For Chronic Pancreatitis In Japanmentioning

confidence: 99%

“…Compared with the results obtained by the secretin-CCK test, the average sensitivity is 79% for the PLT, 71% for the PABA test and 85% for FCT in patients with severe exocrine pancreatic insufficiency, and 39, 46 and 49% in those with mild-moderate exocrine pancreatic insufficiency [13]. The JPS Criteria 1995 employed the BT-PABA test and the FCT for the diagnosis of probable chronic pancreatitis [10,11]. In 1995, however, a new ELISA became commercially available to measure human specific elastase-1 concentration Otsuki Fig.…”

Section: Diagnostic Criteria For Chronic Pancreatitis In Japanmentioning

confidence: 99%

“…ERP or endoscopic retrograde cholangiopancreatography (ERCP) is considered as a sensitive and specific test for the diagnosis of chronic pancreatitis in the absence of tissue confirmation. The criteria also emphasized the importance of ERP findings of irregular dilatation of the lateral side branches with scattered distribution throughout the pancreas for the diagnosis of definite chronic pancreatitis [10,11]. However, ERCP is a technically difficult procedure, with failure rates of 3 to 10% [16,17] and an invasive method that can potentially cause severe complications such as pancreatitis [18][19][20].…”

Section: Diagnostic Criteria For Chronic Pancreatitis In Japanmentioning

confidence: 99%

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Chronic pancreatitis

Ōtsuki

2004

Pancreatology

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“…Chronic pancreatitis was diagnosed according to the 1983 criteria of the Japan Pancreas Society (4). The criteria were revised in 1995 (5), but the diagnosis in these patients was not affected by the change in criteria. In brief, one or more of the following criteria were fulfilled: histological findings compatible with chronic pancreatitis; detection of pancreatic calcification; abnormal exocrine pancreatic function on the pancreozymin/ secretin test or the secretin test; and abnormalities of the pancreatic duct and/or pancreas on imaging studies.…”

Section: Introductionmentioning

confidence: 99%

Pancreatic Carcinoma Associated with Chronic Pancreatitis.

et al. 1999

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The incidence of invasive ductal carcinoma of the pancreas was 3.1 % (6 cases) in 196 patients with definite chronic pancreatitis. Five patients (3 men and 2 women) had calcific pancreatitis and 1 patient (man) had non-calcific pancreatitis. Large pancreatic stones were recognized in 2 women.Most of the patients complained of continuous intractable abdominal pain and/or back pain together with weight loss and appetite loss. Serum CA19-9levels and exacerbation of glucose intolerance were retrospectively noted to have been elevated in 1 patient. However, it was difficult to obtain a definitive diagnosis by imaging examinations earlier, due to the presence of chronic pancreatitis. Median survival of the 6 patients was 6.5 months from admission. (Internal Medicine 38: 951-956, 1999)

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Diagnostic Criteria for Chronic Pancreatitis by the Japan Pancreas Society

Cited by 125 publications

References 0 publications

Distinct Clinical Features of Two Patients That Progressed from the Early Phase of Chronic Pancreatitis to the Advanced Phase

Distinct Clinical Features of Two Patients That Progressed from the Early Phase of Chronic Pancreatitis to the Advanced Phase

Chronic pancreatitis

Pancreatic Carcinoma Associated with Chronic Pancreatitis.

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