Diagnostic criteria for Menière's disease

Lopez-Escamez, José A.; Carey, John P.; Chung, Won Ho; Goebel, Joel A.; Magnusson, Måns; Mandalà, Marco; Newman‐Toker, David E.; Strupp, Michael; Suzuki, Mamoru; Trabalzini, Franco; Bisdorff, Alexandre

doi:10.3233/ves-150549

Cited by 1,137 publications

(832 citation statements)

References 45 publications

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“…According to the cochlear traveling-wave model first described by Von Bekesy, the base of the cochlea is sensitive to high-frequency sounds, whereas its apex is more sensitive to lower-frequency sounds [17]. Our finding of higher outer hair cell loss in the apical turn of samples in our syphilis group is consistent with low-frequency hearing loss, which is a common symptom of Meniere’s disease [18, 19]. …”

Section: Discussionsupporting

confidence: 81%

Stria vascularis and cochlear hair cell changes in syphilis: A human temporal bone study

et al. 2016

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Objective To observe any changes in stria vascularis and cochlear hair cells in patients with syphilis Materials and Methods We examined 13 human temporal bone samples from 8 patients with syphilis (our syphilis group), as well as 12 histopathologically normal samples from 9 age-matched patients without syphilis (our control group). We compared, between the 2 groups, the mean area of the stria vascularis (measured with conventional light microscopy connected to a personal computer) and the mean percentage of cochlear hair cell loss (obtained from cytocochleograms). Results In our syphilis group, only 1 (7.7%) of the 13 samples had precipitate in the endolymphatic or perilymphatic spaces; 8 (61.5%) of the samples revealed the presence of endolymphatic hydrops (4 cochlear, 4 saccular). The mean area of the stria vascularis area did not significantly differ, in any turn of the cochlea, between the 2 groups (P > 0.1). However, we did find significant differences between the 2 groups in the mean percentage of outer hair cells in the apical turn (P < 0.026) and in the mean percentage of inner hair cells in the basal (P = 0.001), middle (P = 0.004), and apical (P = 0.018) turns. In 7 samples in our syphilis group, we observed either complete loss of the organ of Corti or a flattened organ of Corti without any cells in addition to the absence of both outer and inner hair cells. Conclusion In this study, syphilis led either to complete loss of the organ of Corti or to significant loss of cochlear hair cells, in addition to cochleosaccular hydrops. But the area of the stria vascularis did not change.

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Section: Discussionsupporting

confidence: 81%

Stria vascularis and cochlear hair cell changes in syphilis: A human temporal bone study

et al. 2016

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“…7,8 Those with Meniere disease, as compared to those without, were more likely to describe their dizziness as vertigo, 86% to 59% (p=.0002). They also strongly indicated duration of attacks as minutes to hours, with 75% choosing this option.…”

Section: Resultsmentioning

confidence: 98%

“…13 This may reflect the strong association of hearing loss and tinnitus with Meniere disease. 7 These conditions are easily recognized by patients and thus the data collection for these variables may be more accurate. Further, the diagnostic criteria for Meniere disease include these conditions thus increasing the probability of Meniere disease when present.…”

Section: Discussionmentioning

confidence: 99%

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Development of a Statistical Model for the Prediction of Common Vestibular Diagnoses

Friedland

Tarima

Erbe

et al. 2016

JAMA Otolaryngol Head Neck Surg

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Importance Vestibular patients are often complex, require additional clinic visit time, and utilize greater clinical resources for diagnosis. A pre-encounter intake questionnaire may predict the most common disorders allowing for more efficient allocation of resources and use of providers. Objective To develop a statistical model for predicting vestibular diagnoses, prior to clinical evaluation, from an intake questionnaire. Design, Setting and Participants Retrospective review of 414 new vestibular patient intake questionnaires and medical records with performance of logistic regression analyses and development of predictive models. Intervention Use of a vestibular intake questionnaire for triaging of new patients with complaints of dizziness. Main Outcome Measures Predictors for the diagnosis of BPPV, Meniere disease, and vestibular migraine. Results Ear-related disorders accounted for 48% of all diagnoses while neurologic conditions accounted for 37% of diagnoses. Three disorders – benign paroxysmal positional vertigo (BPPV), Meniere disease and vestibular migraine – comprised 69% of all diagnoses. The diagnosis of BPPV could be predicted from four variables with a sensitivity of 79% and specificity of 65%. The diagnosis of Meniere disease could be predicted from five variables with a sensitivity of 81% and specificity of 85%. The diagnosis of vestibular migraine could be predicted from four variables with a sensitivity of 76% and specificity of 59%. Conclusions A pre-encounter history questionnaire can provide useful diagnostic information for common vestibular disorders. This can help direct appointment scheduling to improve clinical efficiency, time to intervention, and use of resources. Further refinement may enable shorter questionnaires or screening algorithms.

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“…Histopathologic examination in patients with MD shows a distention of Reissner’s membrane (endolymphatic hydrops) in the cochlea or endolymphatic compartment of the labyrinth (3, 4). Since histopathologic examination (the gold standard) is not possible in a clinical setting, the diagnosis depends on the symptoms of MD (1, 5). For the diagnosis of definite MD, one of the criteria is that other causes of the symptoms have been excluded.…”

Section: Introductionmentioning

confidence: 99%

An Exploratory Study to Detect Ménière’s Disease in Conventional MRI Scans Using Radiomics

et al. 2016

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ObjectiveThe purpose of this exploratory study was to investigate whether a quantitative image analysis of the labyrinth in conventional magnetic resonance imaging (MRI) scans using a radiomics approach showed differences between patients with Ménière’s disease (MD) and the control group.Materials and methodsIn this retrospective study, MRI scans of the affected labyrinths of 24 patients with MD were compared to the MRI scans of labyrinths of 29 patients with an idiopathic asymmetrical sensorineural hearing loss. The 1.5- and 3-T MRI scans had been previously made in a clinical setting between 2008 and 2015. 3D Slicer 4.4 was used to extract several substructures of the labyrinth. A quantitative analysis of the normalized radiomic image features was performed in Mathematica 10. The image features of the two groups were statistically compared.ResultsFor numerous image features, there was a statistically significant difference (p-value <0.05) between the MD group and the control group. The statistically significant differences in image features were localized in all the substructures of the labyrinth: 43 in the anterior semicircular canal, 10 in the vestibule, 22 in the cochlea, 12 in the posterior semicircular canal, 24 in the horizontal semicircular canal, 11 in the common crus, and 44 in the volume containing the reuniting duct. Furthermore, some figures contain vertical or horizontal bands (three or more statistically significant image features in the same image feature). Several bands were seen: 9 bands in the anterior semicircular canal, 1 band in the vestibule, 3 bands in the cochlea, 0 bands in the posterior semicircular canal, 5 bands in the horizontal semicircular canal, 3 bands in the common crus, and 10 bands in the volume containing the reuniting duct.ConclusionIn this exploratory study, several differences were found in image features between the MD group and the control group by using a quantitative radiomics approach on high resolution T2-weighted MRI scans of the labyrinth. Further research should be aimed at validating these results and translating them in a potential clinical diagnostic method to detect MD in MRI scans.

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Diagnostic criteria for Menière's disease

Abstract: This paper presents diagnostic criteria for Menière's disease

Cited by 1,137 publications

References 45 publications

Stria vascularis and cochlear hair cell changes in syphilis: A human temporal bone study

Stria vascularis and cochlear hair cell changes in syphilis: A human temporal bone study

Development of a Statistical Model for the Prediction of Common Vestibular Diagnoses

An Exploratory Study to Detect Ménière’s Disease in Conventional MRI Scans Using Radiomics

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