Diagnostic Performance of 18F-FDG PET/CT for Lymph Node Staging in Penile Cancer

Lee, Sang Woo; Kim, Seong-Jang

doi:10.1097/rlu.0000000000004081

Cited by 9 publications

(2 citation statements)

References 34 publications

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“…However, the presence of palpable inguinal lymph nodes is an indication for inguinal lymph node excision. Recently, a systematic review and metanalysis by Lee et al showed that 18F-FDG PET/CT had a good diagnostic performance for the detection of metastatic lymph nodes, refreshing the role of this imaging modality in the diagnostic work-up of patients with penile carcinoma [18]. The role of 18F-FDG PET/CT in the diagnostic pathway is justified by enhanced anatomical information as compared to the cross-sectional assessment of CT scans.…”

Section: Indications For Pelvic Lymph Node Dissectionmentioning

confidence: 99%

“…detection of metastatic lymph nodes, refreshing the role of this imaging modality in the diagnostic work-up of patients with penile carcinoma [18]. The role of 18F-FDG PET/CT in the diagnostic pathway is justified by enhanced anatomical information as compared to the cross-sectional assessment of CT scans.…”

Section: Anatomical Considerations Of Pelvic Lymph Node Dissectionmentioning

confidence: 99%

See 1 more Smart Citation

Prophylactic Lymphadenectomy in Patients with Penile Cancer: Is Sooner Better?

Cai,

Capece,

Zorzi

et al. 2023

Uro

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Background: Management of penile cancer patients has its grey zones. In particular, no strong evidence or recommendations exist regarding the timing of prophylactic lymphadenectomy. Here, we aim to review the impact that the timing of inguinal and pelvic prophylactic lymph node dissection has on patient outcome. Methods: All relevant databases were searched following the preferred reporting items for systematic reviews and meta-analysis guidelines. A narrative review of indications for lymph node dissection and pathological considerations precede a systematic review of the impact of prophylactic lymph node dissection timing on prognosis. The primary endpoint is disease-free and overall survival in patients undergoing early or late lymph node dissection after penile cancer diagnosis. Results: Four clinical trials, all focusing on the role of inguinal lymph node dissection, are included. Despite the lack of randomized and controlled trials, this review suggests that lymph node dissection should be performed as soon as possible after diagnosis, with 3 months as a realistic cut-off. Conclusions: Survival of penile cancer patients is strictly related to the timing of prophylactic pelvic lymph node dissection. All patients at high risk of nodal metastasis should be offered lymph node dissection within three months of diagnosis, until new predicting tools are validated.

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Section: Indications For Pelvic Lymph Node Dissectionmentioning

confidence: 99%

Section: Anatomical Considerations Of Pelvic Lymph Node Dissectionmentioning

confidence: 99%