Diagnostic Performance of Contrast Enhanced CT Alone or in Combination with (Non-)Enhanced MRI for Colorectal Liver Metastasis

Qiu, Qian-Sai; Zhu, Kai; Wang, Jiahui; Chen, Xiaoshan; Wang, Wentao; Dong, San-Yuan; Sun, Wei; Rao, Sheng-Xiang

doi:10.1016/j.acra.2022.11.011

Cited by 1 publication

(1 citation statement)

References 36 publications

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“…About 50% of the dose of gadoxetate disodium (Eovist ® , Bayer HealthCare, Whippany, NJ, USA) is excreted through the hepatobiliary pathway and enables the acquisition of functional post-contrast MRCP images, providing a more detailed assessment of the biliary tree [24,25]. The increased diagnostic accuracy of MRI over CT for CLM has been demonstrated through multiple meta-analyses with the perlesion specificity ranging from 86.9 to 100%, and according to the latest (1.2024) NCCN guidelines for Colon Cancer, liver CE-MRI is recommended over CT to evaluate the exact number and distribution of metastatic foci for local treatment planning, when surgery or liver-directed therapy is considered [8,22,[26][27][28]. Definitive evidence on the additional value of CE-MRI and DWI-MRI to CT in the routine investigation of patients with CLM, who are scheduled to undergo local treatment based on CT findings alone, came from the CAMINO study [29].…”

Section: Baseline Imaging Prior To Locoregional Treatmentmentioning

confidence: 99%

Imaging Considerations before and after Liver-Directed Locoregional Treatments for Metastatic Colorectal Cancer

Chlorogiannis,

Moussa,

Zhao

et al. 2024

Diagnostics

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Colorectal cancer is a leading cause of cancer-related death. Liver metastases will develop in over one-third of patients with colorectal cancer and are a major cause of morbidity and mortality. Even though surgical resection has been considered the mainstay of treatment, only approximately 20% of the patients are surgical candidates. Liver-directed locoregional therapies such as thermal ablation, Yttrium-90 transarterial radioembolization, and stereotactic body radiation therapy are pivotal in managing colorectal liver metastatic disease. Comprehensive pre- and post-intervention imaging, encompassing both anatomic and metabolic assessments, is invaluable for precise treatment planning, staging, treatment response assessment, and the prompt identification of local or distant tumor progression. This review outlines the value of imaging for colorectal liver metastatic disease and offers insights into imaging follow-up after locoregional liver-directed therapy.

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