Diagnostic Performance of Dobutamine Stress Echocardiography in End-Stage Liver Disease

Doytchinova, Anisiia; Feigenbaum, Thomas D.; Pondicherry-Harish, Roja; Sepanski, Peter; Green-Hess, Deborah; Feigenbaum, Harvey; Sawada, Stephen

doi:10.1016/j.jcmg.2018.10.031

Cited by 24 publications

(24 citation statements)

References 25 publications

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“…The sensitivity and specificity of DopSE was 45% and 88% (Table 4). We have previously shown that DSE sensitivity in ALD patients is higher in those with LV cavity dimension >4.8 cm 4 . In patients with diastolic cavity dimension <4.8, DopSE sensitivity and specificity were 38% (3/8) and 87% (13/15).…”

Section: Resultsmentioning

confidence: 89%

“…Further reduction in preload and afterload can produce hypotension, inadequate stress, and marked reduction of test sensitivity. At our own institution, DSE was found to have a sensitivity of 24% for obstructive coronary disease in patients with ALD 4 . Dopamine may be a more effective stress agent than dobutamine because of alpha adrenergic–mediated vasoconstrictive effects that could result in higher RPP and wall stress 5‐7 .…”

Section: Introductionmentioning

confidence: 94%

“…There were no serious adverse events with either stress test, as defined by arrhythmias, allergic reaction, IV infiltration, or skin ne- ALD. 4 In 76% of these exams, the target heart rate was achieved. The peak heart rate with DopSE was again significantly higher than with DSE (146 ± 18 bts/min vs 138 ± 15 bts/min, P < .001).…”

Section: Re Sultsmentioning

confidence: 99%

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Safety and feasibility of dopamine‐atropine stress echocardiography

et al. 2021

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Dobutamine-atropine stress echocardiography (DSE) is a widely employed pharmacologic stress test. 1 Dobutamine stress increases myocardial oxygen demand in a similar but not identical fashion to exercise. Both modalities increase heart rate, but reductions in preload and afterload by dobutamine stress may result in lower rate pressure product (RPP) and reduced efficacy of DSE. 2 The beta-2 receptor stimulating effect of dobutamine may result in marked reductions of preload and systemic vascular resistance in certain

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Section: Resultsmentioning

confidence: 89%

Section: Introductionmentioning

confidence: 94%

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Safety and feasibility of dopamine‐atropine stress echocardiography

et al. 2021

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“…Five studies (1243 participants) identified DSE (Donovan 1996, Harinstein 2008, Sinpelisky 2014, Doytchinova 2019, Kutkut 2019) [27] , [28] , [29] , [30] , [31] . Presence of wall motion abnormalities during the stress test was considered a positive result for diagnosing CAD ( Fig.…”

Section: Resultsmentioning

confidence: 99%

Diagnostic accuracy of cardiac testing for coronary artery disease in potential liver transplant recipients: A systematic review and meta-analysis

Tiwari

Margapuri

Katamreddy

et al. 2021

IJC Heart & Vasculature

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“…Low sensitivity has also been found in a larger scale study published recently. In this investigation, 633 patients who had undergone both dobutamine SE and coronary angiography were included [74]. Sensitivity was calculated at 24%, meaning that less than one out of four patients with hemodynamically significant coronary artery stenosis, had a positive SE.…”

Section: Stress Echocardiography In Lt Candidates Current Knowledgementioning

confidence: 99%

Cardiac Imaging in Liver Transplantation Candidates: Current Knowledge and Future Perspectives

Dimitroglou

Aggeli

Alexopoulou

et al. 2019

JCM

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Cardiovascular dysfunction in cirrhotic patients is a recognized clinical entity commonly referred to as cirrhotic cardiomyopathy. Systematic inflammation, autonomic dysfunction, and activation of vasodilatory factors lead to hyperdynamic circulation with high cardiac output and low peripheral vascular resistance. Counter acting mechanisms as well as direct effects on cardiac cells led to systolic or diastolic dysfunction and electromechanical abnormalities, which are usually masked at rest but exposed at stress situations. While cardiovascular complications and mortality are common in patients undergoing liver transplantation, they cannot be adequately predicted by conventional cardiac examination including transthoracic echocardiography. Newer echocardiography indices and other imaging modalities such as cardiac magnetic resonance have shown increased diagnostic accuracy with predictive implications in cardiovascular diseases. The scope of this review was to describe the role of cardiac imaging in the preoperative assessment of liver transplantation candidates with comprehensive analysis of the future perspectives anticipated by the use of newer echocardiography indices and cardiac magnetic resonance applications.

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Diagnostic Performance of Dobutamine Stress Echocardiography in End-Stage Liver Disease

Cited by 24 publications

References 25 publications

Safety and feasibility of dopamine‐atropine stress echocardiography

Safety and feasibility of dopamine‐atropine stress echocardiography

Diagnostic accuracy of cardiac testing for coronary artery disease in potential liver transplant recipients: A systematic review and meta-analysis

Cardiac Imaging in Liver Transplantation Candidates: Current Knowledge and Future Perspectives

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