Diagnostic performance of MR black-blood thrombus imaging for cerebral venous thrombosis in real-world clinical practice

Wu, Fang; Liu, Yuehong; Duan, Jiangang; Fisher, Marc; Ji, Xunming; Meng, Ran; Zhang, Huibo; Fan, Zhaoyang; Yang, Qi

doi:10.1007/s00330-021-08286-x

Cited by 11 publications

(7 citation statements)

References 38 publications

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“…Although the 3D T1W BrainVIEW sequence has reportedly been used to observe arterial lesions, 16,17 it has not been used to study CVT. Based on the experience of applying magnetic resonance black-blood thrombus imaging technology (a variable flipangle 3D TSE sequence similar to 3D T1W BrainVIEW) to CVT MRI on Siemens 3.0 T MRI equipment, [23][24][25] we used a 3D T1W BrainVIEW sequence to perform a wholebrain venous scan. In the examination of our patient with suspected CVT, we used the 3D T1W BrainVIEW sequence to perform the whole-brain venous scan.…”

Section: Discussionmentioning

confidence: 99%

Clinical application of three-dimensional T1-weighted BrainVIEW in magnetic resonance imaging of cerebral venous thrombosis: a case report and literature review

Yang¹,

Huang

Hu³

et al. 2023

J Int Med Res

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To date, there is no clinical scoring system or laboratory indicator that can rule out cerebral venous thrombosis (CVT) or provide diagnostic proof for evaluating post-treatment thrombosis recanalization during follow-up. We therefore explored an imaging method for quantitative assessment of CVT and assessed thrombotic changes during follow-up. A patient presented with severe posterior occipital distension extending to the top of the forehead and an elevated plasma D-dimer (DD2) level. Computed tomography and pre-contrast-enhanced magnetic resonance imaging revealed only a small amount of cerebral hemorrhage. Three-dimensional (3D) T1-weighted (T1W) BrainVIEW pre-contrast-enhanced magnetic resonance scanning showed subacute thrombosis in the venous sinus, and the post-contrast-enhanced scan combined with volume rendering reconstruction showed cerebral thrombosis of the venous sinus and allowed for measurement of the thrombus volume. On days 30 and 60 of post-treatment follow-up, post-contrast-enhanced scans showed progressive reduction of the thrombus volume as well as recanalization and fibrotic flow voids in the chronic thrombosis. 3D T1W BrainVIEW was helpful to observe the size of the thrombi and the situation of venous sinus recanalization during the follow-up after clinical treatment of CVT. This technique can reflect the imaging manifestations of CVT throughout the whole process to guide clinical treatment decisions.

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Section: Discussionmentioning

confidence: 99%

Clinical application of three-dimensional T1-weighted BrainVIEW in magnetic resonance imaging of cerebral venous thrombosis: a case report and literature review

Yang¹,

Huang

Hu³

et al. 2023

J Int Med Res

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“…Venous thrombosis appears as heterogeneous signal intensity within the dark lumen of the venous sinus. MR VWI has shown excellent diagnostic value in acute CVST [ 68 , 69 ], and can be used to predict treatment response to endovascular therapy [ 70 ]. Given that this diagnostic tool is non-invasive, radiation-free, and highly accurate, MR VWI may be optimal for the longitudinal evaluation of post-traumatic vasculopathies; however, imaging protocols are not widely used in current clinical practice.…”

Section: Diagnosismentioning

confidence: 99%

Post-Traumatic Cerebral Infarction: A Narrative Review of Pathophysiology, Diagnosis, and Treatment

Poblete,

Zhong,

Patel

et al. 2024

Neurology International

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Traumatic brain injury (TBI) is a common diagnosis requiring acute hospitalization. Long-term, TBI is a significant source of health and socioeconomic impact in the United States and globally. The goal of clinicians who manage TBI is to prevent secondary brain injury. In this population, post-traumatic cerebral infarction (PTCI) acutely after TBI is an important but under-recognized complication that is associated with negative functional outcomes. In this comprehensive review, we describe the incidence and pathophysiology of PTCI. We then discuss the diagnostic and treatment approaches for the most common etiologies of isolated PTCI, including brain herniation syndromes, cervical artery dissection, venous thrombosis, and post-traumatic vasospasm. In addition to these mechanisms, hypercoagulability and microcirculatory failure can also exacerbate ischemia. We aim to highlight the importance of this condition and future clinical research needs with the goal of improving patient outcomes after TBI.

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“…The vessel wall MRI is a black-blood scanning method 20 using sequences of two-dimensional T2-weighted MultiVane XD turbo spin-echo (2D-T2-MVXD-TSE) 22,23 and three-dimensional T1-weighted motion sensitized driven equilibrium fat suppression turbo spin-echo (3D-T1-MSDE-TSE) sequences. 19 The sequence parameters for both conventional and vessel wall imaging are presented in Table 1. The total scan time of the protocol with conventional and vessel wall imaging sequences together was approximately: 40-45 minutes.…”

Section: Mri Protocolmentioning

confidence: 99%

“…17,18 Vessel wall MRI has also been used for imaging the vasculatures of the thorax and abdomen to detect abdominal aortic aneurysms and to characterize lumen embolus. 19,20 Therefore, this technique can be potentially applied to detect and assess vascular invasion of retroperitoneal tumors in order to provide radiological information for the development of a treatment plan and preoperative evaluation if the patient is qualified for surgery. 21 We hypothesized that non-contrast-enhanced vessel wall MRI would have a better capability to investigate the invasiveness and degree of the tumor to the blood vessels than conventional MRI.…”

mentioning

confidence: 99%

Value of Non‐Contrast‐Enhanced Vessel Wall MR Imaging in Assessing Vascular Invasion of Retroperitoneal Tumors

Cui,

Zhao,

Chen

et al. 2023

Magnetic Resonance Imaging

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BackgroundDue to their location and growth patterns, retroperitoneal tumors often involve the surrounding blood vessels. Clinical decisions on a proper treatment depend on the information on this condition. Evaluation of blood vessels using non‐contrast‐enhanced vessel wall MRI may provide noninvasive assessment of the extent of tumor invasion to assist clinical decision‐making.PurposeTo investigate the performance and potential of non‐contrast‐enhanced vessel wall MRI in evaluating the degree of vessel wall invasion of retroperitoneal tumors.Study TypeProspective.PopulationThirty‐seven participants (mean age: 60.59 ± 11.77 years, 59% male) with retroperitoneal tumors close to vessels based on their diagnostic computer tomography.Field Strength/Sequences3 T; vessel wall MRI sequences: two‐dimensional T2‐weighted MultiVane XD turbo spin‐echo (2D‐T2‐MVXD‐TSE) and three‐dimensional T1‐weighted motion sensitized driven equilibrium fat suppression turbo spin‐echo (3D‐T1‐MSDE‐TSE) sequences; conventional MRI sequences: T2‐weighted fat suppression turbo spin‐echo (T2‐FS‐TSE), T2‐weighted turbo spin‐echo (T2‐TSE), modified Dixon T1‐weighted fast field echo (T1‐mDixon‐FFE), and diffusion‐weighted echo planar imaging (DWI‐EPI) sequences.AssessmentAll patients underwent preoperative imaging using both non‐contrast conventional and vessel wall MRI sequences. Images obtained from conventional and vessel wall MRI sequences were evaluated independently by three junior radiologists (3 and 2 years of experience in reading MRI) and reviewed by one senior radiologist (25 years of experience in reading MRI) to assess the degree of vessel wall invasion. MRI were validated results from the clinical standard diagnosis based on surgical confirmation or histopathological reports. Interobserver agreement was determined based on the reports from three readers with similar years of experiences. Intraobserver variability was assessed based on categorizing and recategorizing the vessels of 37 patients 1 month apart.Statistical TestsIntra‐class correlation efficient (ICC), Chi‐square test, McNemar test, area under the receiver‐operating characteristic curve (AUC), Delong test, P < 0.05 was considered significant.ResultsThe accuracy of vessel wall MRI (91.96%, 95% CI: 85.43–95.71; 103 of 112) in detecting the degree of vessel wall invasion was significantly higher than that of conventional MRI (75%, 95% CI: 66.24–82.10; 84 of 112). The interobserver variability or reproducibility in categorization of the degree of vascular wall invasion was good in evaluating images from conventional and vessel wall MRI sequences (ICC = 0.821, 95% CI: 0.765–0.867 and ICC = 0.881, 95% CI: 0.842–0.913, respectively).Data ConclusionDiagnosis of vessel wall invasion of retroperitoneal tumors and assessment of its severity can be improved by using non‐contrast‐enhanced vessel wall MRI.Evidence Level1Technical EfficacyStage 3

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Diagnostic performance of MR black-blood thrombus imaging for cerebral venous thrombosis in real-world clinical practice

Cited by 11 publications

References 38 publications

Clinical application of three-dimensional T1-weighted BrainVIEW in magnetic resonance imaging of cerebral venous thrombosis: a case report and literature review

Clinical application of three-dimensional T1-weighted BrainVIEW in magnetic resonance imaging of cerebral venous thrombosis: a case report and literature review

Post-Traumatic Cerebral Infarction: A Narrative Review of Pathophysiology, Diagnosis, and Treatment

Value of Non‐Contrast‐Enhanced Vessel Wall MR Imaging in Assessing Vascular Invasion of Retroperitoneal Tumors

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