Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA)

Pierucci‐Lagha, Amira; Gelernter, Joel; Feinn, Richard; Cubells, Joseph F.; Pearson, Deborah; Pollastri, Alisha R.; Farrer, Lindsay A.; Kranzler, Henry R.

doi:10.1016/j.drugalcdep.2005.04.005

Cited by 193 publications

(231 citation statements)

References 24 publications

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“…In that study, the SSADDA yielded good-to-excellent reliabilities for most substance dependence diagnoses, although the reliability of substance abuse diagnoses was not as good (Pierucci-Lagha et al, 2005). The present report describes the reliability of the DSM-IV diagnostic criteria obtained using the SSADDA.…”

Section: Introductionmentioning

confidence: 63%

“…Conclusions-These results, combined with results from a study of the SSADDA's diagnostic reliability (Pierucci-Lagha et al, 2005), show that the instrument can be used reliably to assess substance dependence.…”

Section: Introductionmentioning

confidence: 78%

“…To enhance the reliability of the psychiatric diagnostic process, particularly as it pertains to psychiatric genetics, several structured or semi-structured interviews have been developed, including the Diagnostic Interview for Genetic Studies (DIGS; Nurnberger et al, 1994), the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA; Bucholz et al, 1995), and the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA; Pierucci-Lagha et al, 2005). Bucholz et al (1995) evaluated the diagnostic reliability of the SSAGA using DSM-III-R criteria (American Psychiatric Association, 1987), in a sample with a high prevalence of alcohol use disorders.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, we evaluated the inter-rater and test-retest reliabilites of DSM-IV diagnoses obtained with the SSADDA in a diverse sample of subjects, in which there was a high prevalence of cocaine-and/or opioid-dependent individuals (Pierucci-Lagha et al, 2005). In that study, the SSADDA yielded good-to-excellent reliabilities for most substance dependence diagnoses, although the reliability of substance abuse diagnoses was not as good (Pierucci-Lagha et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

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Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA)

Pierucci‐Lagha

Gelernter

Chan

et al. 2007

Drug and Alcohol Dependence

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132

139

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The Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA) yields reliable DSM-IV diagnoses for a variety of psychiatric disorders, including alcohol and drug dependence. This study examines the reliability of individual DSM-IV criteria for lifetime substance dependence diagnoses and the impact of those criteria on diagnostic reliability.Methods-Two hundred ninety-three subjects (52.2% women; 38.2% African American, 46.8% European American, 7.5% Hispanic) were interviewed twice over a two-week period to examine the inter-rater reliability (n = 173) or test-retest reliability (n = 120) of the SSADDA. Cohen's κ statistic and its confidence interval were used to assess the reliability of individual diagnostic criteria.Results-Overall, the inter-rater reliability estimates were excellent for individual DSM-IV criteria for nicotine and opioid dependence; good for alcohol and cocaine dependence, and fair for dependence on cannabis, sedatives and stimulants. The impact of any individual criterion on diagnostic reliability was minimal, consistent with the notion that the DSM-IV diagnosis of substance dependence measures an underlying construct that is relatively consistent across specific groups of substances.Conclusions-These results, combined with results from a study of the SSADDA's diagnostic reliability (Pierucci-Lagha et al., 2005), show that the instrument can be used reliably to assess substance dependence.

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Section: Introductionmentioning

confidence: 63%

Section: Introductionmentioning

confidence: 78%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA)

Pierucci‐Lagha

Gelernter

Chan

et al. 2007

Drug and Alcohol Dependence

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132

139

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“…Subjects previously examined at the CNR1 (AAT)n marker by our group (Covault et al 2001) were included in the current sample and represent 38% of the 1,367 subjects examined here. Psychiatric diagnoses were made using the Structured Clinical Interview for DSM-III-R or DSM-IV (SCID) (First et al 1997) or the Semi-Structured Assessment for Drug Dependence and Alcoholism Pierucci-Lagha et al 2005). Substance dependent subjects with a lifetime diagnosis of schizophrenia were excluded.…”

Section: Subjectsmentioning

confidence: 99%

Association study of the CNR1 gene exon 3 alternative promoter region polymorphisms and substance dependence

Herman

Kranzler

Cubells

et al. 2006

American J of Med Genetics Pt B

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An alternative promoter producing a novel 5′-untranslated region of cannabinoid receptor mRNA has recently been described in CNR1, the gene encoding the cannabinoid receptor protein. Single nucleotide polymorphisms (SNPs) adjacent to this site were reported to be associated with polysubstance abuse (Zhang et al. 2004). We examined the association of 4 SNPs (rs6928499, rs806379, rs1535255, rs2023239) in the distal region of intron 2 of CNR1 both with individual substance dependence diagnoses (i.e., alcohol, cocaine, and opioids), as well as with polysubstance dependence. The study samples consisted of European American and African American subjects with drug and or alcohol dependence (n=895), and controls (n = 472). Subjects were grouped as polysubstance dependent, opioid dependent, cocaine dependent, cannabis dependent and alcohol dependent. There was a modest association of marker rs1535255 with alcohol dependence, respectively (P=0.04), though with correction for multiple phenotype comparisons, this effect was not considered statistically significant. These findings fail to replicate the original report of an association between SNPs adjacent to an alternative CNR1 exon 3 transcription start site and polysubstance abuse.

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Association of Variants in MANEA With Cocaine-Related Behaviors

Farrer¹,

Kranzler²,

Yu³

et al. 2009

Arch Gen Psychiatry

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Context Cocaine dependence (CD) and related behaviors are highly heritable, but no genetic association has been consistently demonstrated. A recent genome-wide study of drug dependence identified an association between cocaine-induced paranoia (CIP) and a single-nucleotide polymorphism (SNP) in the α-endomannosidase (MANEA) locus in a family-based sample of European Americans and African Americans. Objective To conduct a comprehensive genetic association study of the MANEA locus with CD and CIP. Design Genome-wide association study. Setting Four university hospitals. Participants A total of 3992 individuals from 2 family-based and 2 case-control samples. Intervention Participants were classified as having CD or CIP or as a control using the Semi-Structured Assessment for Drug Dependence and Alcoholism. They were genotyped for 11 SNPs spanning MANEA and its surrounding region. Main Outcome Measure Association of CD and CIP with individual SNPs and haplotypes. Results Cocaine-induced paranoia was associated with 6 SNPs in the European American families and 9 SNPs in the African American families. The strongest evidence in the total sample of families was observed in 3 markers located in the promoter and 3′ untranslated regions (P < .001). The association of MANEA SNPs with CD in both family samples was much weaker. In the African American case-control sample, multiple markers were significantly associated with CIP and CD; CIP and CD were also significantly associated with a 2-SNP haplotype in the European American case-control sample. The A allele of the 3′ untranslated region SNP rs9387522 was associated with increased risk of CIP in all 4 data sets. Conclusions Our findings suggest that CD and associated behaviors may involve biological pathways not typically thought to be associated with brain metabolism.

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Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA)

Cited by 193 publications

References 24 publications

Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA)

Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA)

Association study of the CNR1 gene exon 3 alternative promoter region polymorphisms and substance dependence

Association of Variants in MANEA With Cocaine-Related Behaviors

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