2024
DOI: 10.4240/wjgs.v16.i7.2003
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Diagnostic significance of serum levels of serum amyloid A, procalcitonin, and high-mobility group box 1 in identifying necrotising enterocolitis in newborns

Li-Ming Guo,
Zhi-Hui Jiang,
Hong-Zhen Liu
et al.

Abstract: BACKGROUND Necrotising enterocolitis (NEC) is a critical gastrointestinal emergency affecting premature and low-birth-weight neonates. Serum amyloid A (SAA), procalcitonin (PCT), and high-mobility group box 1 (HMGB1) have emerged as potential biomarkers for NEC due to their roles in inflammatory response, tissue damage, and immune regulation. AIM To evaluate the diagnostic value of SAA, PCT, and HMGB1 in the context of NEC in newborns. METHODS The study retrosp… Show more

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