Diagnostic test of endometrial cytobrush in cases of perimenopausal and postmenopausal hemorrhage

Andrijono, Andrijono; Prayitno, G.D.; Hamdani, Chairil

doi:10.13181/mji.v14i2.181

Med J Indones

2005

DOI: 10.13181/mji.v14i2.181

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Diagnostic test of endometrial cytobrush in cases of perimenopausal and postmenopausal hemorrhage

Andrijono Andrijono¹,

G.D. Prayitno²,

Chairil Hamdani³

Abstract: Abstrak

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2019

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Endometrial Cytology as a Method to Improve the Accuracy of Diagnosis of Endometrial Cancer: Case Report and Meta-Analysis

Wang

Zhao

et al. 2019

Front. Oncol.

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More and more researchers have reported that dilatation and curettage (D&C) or Pipelle had low accuracy, high misdiagnosis, and insufficient rate. Endometrial cytology is often compared with histology and seems to be an efficient method for the diagnosis of endometrial disorders, especially endometrial cancer. We report a case of misdiagnosed endometrial cancer by D&C, but with a positive cytopathological finding. Following that, a meta-analysis including 4,179 patients of endometrial diseases with cyto-histopathological results was performed to assess the value of the endometrial cytological method in endometrial cancer diagnosis. The pooled sensitivity and specificity of the cytological method in detecting endometrial atypical hyperplasia or cancer was 0.91[95% confidence interval (CI) 0.74–0.97] and 0.96 (95% CI 0.90–0.99), respectively. The pooled positive likelihood ratio and negative likelihood ratio was 25.4 (95% CI 8.1–80.1) and 0.10 (95% CI 0.00–0.30), respectively. The diagnostic odds ratio which was usually used to evaluate the diagnostic test performance reached 260 (95% CI 36–1905). So we recommend that D&C and Pipelle are still practical procedures to evaluate the endometrium, cytological examinations should be utilized as an additional endometrial assessment method.

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Endometrial Cytology as a Method to Improve the Accuracy of Diagnosis of Endometrial Cancer: Case Report and Meta-Analysis

Wang

Zhao

et al. 2019

Front. Oncol.

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Diagnostic test of endometrial cytobrush in cases of perimenopausal and postmenopausal hemorrhage

Abstract: Abstrak

Cited by 1 publication

References 4 publications

Endometrial Cytology as a Method to Improve the Accuracy of Diagnosis of Endometrial Cancer: Case Report and Meta-Analysis

Endometrial Cytology as a Method to Improve the Accuracy of Diagnosis of Endometrial Cancer: Case Report and Meta-Analysis

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