Diagnostic, therapeutic, and prognostic aspects of typhoid intestinal perforations in Dapaong, Togo

Kassegne, I.; Sewa, E.V.; Kanassoua, K; Alassani, Fousséni; Adabra, Komlan; Amavi, A.K.; Tchangaï, Boyodi; Azialey, KG; Attipou, K

doi:10.1684/mst.2016.0544

Cited by 7 publications

(11 citation statements)

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“…It is superimposed to the 29% of Togola [7] but superior to the 20% of Kambiré I [8]. On the other hand, the frequency of typhus perforations in this study is not comparable to that of Kassegné [2], which observed a frequency of 69.9%. In rural areas.…”

Section: Discussioncontrasting

confidence: 80%

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TyphicIleal Perforation at Kati Chu-BSS for Diagnostic and Therapeutic Aspects (Mali)

Keita¹,

Diarra²,

Keita³

et al. 2021

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Ileal perforation of typhus origin is a common and serious complication of typhoid fever in tropical environments. It is one of the main causes of morbidity in surgery in Mali. However, it would be preventable if salmonellosis were properly managed upstream, and if our living environments were cleaned up. The purpose of this study is to report on the experience of the Kati UHC General Surgery Department in the management of peritonitis by typhic perforation and to assess its prognosis. Patients and Method: This is a retrospective descriptive study that took place from January 2007 to December 2020 in the General Surgery department of the Hospitalo-University BSS Center of Kati (Mali). We have included patients who have undergone peritonitis with confirmed typhic ileal perforation with laparotomy. The other etiologies of peritonitis by ileal perforation were not retained. Results: In 14 years, we collected 89 cases of peritonitis by typhic ileal perforation. It accounted for 3.14% (89/2829) of surgical procedures, 37.5% (89/1181) of visceral surgical emergencies and 27.6% (89/322) of all acute peritonitis causes combined. There were 70 men against 29 women; the sex ratio was 2.4 with an average age of 25.8 years (extremes 8 years to 65 years). Anastomosis resetions (ileo ileal and ileocolic) predominated in 71.8% of patients. However, the ileo stoma was performed in 5.6%. A significant relationship (p 0.05) was observed between high mortality and MPI score > 26. Morbidity was 39.4% with mortality of 15.7%. The average length of stay in hospital was 12.2 days. Conclusion: Typhoid ileal perforation

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Section: Discussioncontrasting

confidence: 80%

“…It is a serious complication of typhoid fever. Its frequency is high in African series [2] [3] however it is a pathology almost unknown in developed countries. Postoperative mortality remains high in sub-Saharan Africa, ranging from 14% to 29.3% [4] [5] mainly due to the late arrival of patients in health facilities.…”

Section: Introductionmentioning

confidence: 99%

TyphicIleal Perforation at Kati Chu-BSS for Diagnostic and Therapeutic Aspects (Mali)

Keita¹,

Diarra²,

Keita³

et al. 2021

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“…[ 6 ] The incidence of typhoid perforation varies from one country to another, but a high rate of 10%–33% has been reported in West Africa with high mortality. [ 4 5 , 8 9 10 12 , 25 ] In our Nigerian context, as in most African countries, TIP is a burden for the predominantly rural population, and its management is a daily activity of the surgeon. [ 1 2 3 4 5 9 , 12 14 , 25 26 27 28 ]…”

Section: Discussionmentioning

confidence: 99%

Typhoid intestinal perforation prognostic score in poor-resource settings

Adamou,

Magagi,

Habou

et al. 2023

J West Afr Coll Surg

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Background: Mortality from peritonitis due to typhoid intestinal perforation (TIP) in sub-Saharan Africa is high. Objectives: This study aimed to determine the predictive factors of mortality, propose a prognostic score, and determine the appropriate surgical treatment for TIP in low-resource settings. Materials and Methods: This was a retrospective data collection of peritonitis due to TIP admitted at Zinder National Hospital from 2014 to 2021. To build a typhoid intestinal perforation prognostic score (TIPPS), patients were randomised into two groups: a score-building group and a validation group. Univariate and multivariate analyses were performed to identify risk factors of mortality. The value of P <0.05 was assigned significant for all analyses. Results: TIP accounted for 52.4% ( n = 1132) of all cases of peritonitis ( n = 2159). The median age was 12 years. Rural provenance represented 72.2% ( n = 817). Deaths accounted for 10.5% ( n = 119). The factors influencing mortality were respiratory rate ≥24/min (odds ratio [OR] = 2.6, P = 0.000), systolic blood pressure <90 mmHg (OR = 0.31, P = 0.002), serum creatinine >20 mg/L (OR = 2.6, P ≤ 0.009), haemoglobin (OR = 2.1, P = 0.000), comorbidity (OR = 3.5, P = 0.001), the American Society of Anesthesiologists score IV&V (OR = 3.3, P = 0.000), admission and management delay > 72 h (OR = 3.2, P = 0.001), and a number of perforations (OR = 2.4, P = 0.0001). These factors were used to build a “TIPPS” score, which ranged from 8 to 20. The risk of mortality was associated with increased TIPPS. The performance of this score was good in the two groups (area under receiver operating characteristic > 0.83). According to the severity and mortality risk of TIP, we classified TIPS into four grades: grade I (low risk: 8–10), grade II (moderate risk: 11–13), grade III (high risk: 14–16) and grade IV (very high risk: 17–20). Conclusion: The TIPPS is simple. It can describe the severity of the disease and can predict the risk of death. The study highlights the importance and impact of timely and adequate perioperative resuscitation in more complicated cases.

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“…However, according to Delabrousse E et al [16] CT has now become the gold standard for abdominal emergencies.…”

Section: Discussionmentioning

confidence: 99%

Contribution of Imaging to the Management of Surgical Emergencies in the General Surgery Department of the Ignace Deen National Hospital

Sandały¹,

Francis²,

Naby³

et al. 2020

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The aim of this work was to eassess the contribution of imaging in the management of non-traumatic abdominal surgical emergencies at the General Surgery Department of the Ignace Deen National Hospital. Material and methods: This was a prospective, descriptive study that included for 6 months all patients admitted and operated for a non-traumatic abdominal surgical emergency and having performed at least one imaging test. Results: During our study period, Non-traumatic abdominal surgical emergencies accounted for 25.27% of admissions. The average age was37.58 years old with a male predominance (65.3%) and a sex ratio of 1.88. The mean consultation time was 66.92h±40.15. PSA was the most performed imaging test (86.44%) followed by abdominal ultrasound (8.47%). The main non-traumatic abdominal surgical emergencies observed were acute generalized peritonitis (45.8%), followed by acute intestinal obstruction (44.1%). The agreement between imaging and operative diagnosis was 93.46% on PSA, 92.86% on abdominal ultrasound and 100% on abdominal CT. Conclusion: Non-traumatic abdominal surgical emergencies are frequent, imaging examinations (ASP, ultrasound) allow a good appreciation of all non-traumatic abdominal emergencies when they are judiciously used. In addition, CT, although essential, remains inaccessible due to its cost, thus limiting its emergency use.

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Diagnostic, therapeutic, and prognostic aspects of typhoid intestinal perforations in Dapaong, Togo

Cited by 7 publications

References 0 publications

TyphicIleal Perforation at Kati Chu-BSS for Diagnostic and Therapeutic Aspects (Mali)

TyphicIleal Perforation at Kati Chu-BSS for Diagnostic and Therapeutic Aspects (Mali)

Typhoid intestinal perforation prognostic score in poor-resource settings

Contribution of Imaging to the Management of Surgical Emergencies in the General Surgery Department of the Ignace Deen National Hospital

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