“…The clinical literature suggests that intermittent cycles of repeated cocaine dosing, that is, binges, followed by abrupt cessation of cocaine use are associated with patterns of withdrawal symptoms and signs (Brower, Maddahian, Blow, & Beresford, 1988; Resnick & Schuyten-Resnick, 1976; Siegel, 1982; Smith, 1984; Trinkoff, Ritter, & Anthony, 1990). Gawin and Kleber (1986) proposed a three-phase model of cocaine abstinence for drug users who self-administer high doses of cocaine in binges based on interviews with cocaine users.…”