Diagnostic use of recombinant human thyrotropin in patients with thyroid carcinoma (phase I/II study).

The diagnostic use of the rhTSH/thyroglobulin test in differentiated thyroid cancer patients with persistent disease and low thyroglobulin levels

“…AUC, area under the curve of measured serum TSH values. effects (Braverman et al ., 1992;Meier et al ., 1994;Dow et al ., 1997;Ladenson et al ., 1997;Haugen et al ., 1999;Pacini & Lippi, 1999;Schlumberger et al, 1999Schlumberger et al, , 2000Robbins et al, 2001). Serum Tg measurement after THST withdrawal has been recently reported to have a higher sensitivity than serum Tg stimulated after rhTSH , although not everyone agrees on this point (Haugen et al, 1999).…”

The use of recombinant human TSH in the follow‐up of differentiated thyroid cancer: experience from a large patient cohort in a single centre

“…The serum TSH levels reached after rhTSH administration were constantly in the potent stimulation range; in particular, TSH levels > 30 mIU/ l were already reached after the first administration of rhTSH in most cases. Furthermore, because of the more rapid clearance of radioiodine in euthyroidism vs. hypothyroidism (Meier et al , 1994;Park et al , 1996), another advantage presented by rhTSH might be its capacity to reduce radiation exposure of healthy tissue.…”

Diagnostic value of serum thyroglobulin measurements in the follow‐up of differentiated thyroid carcinoma, a structured meta‐analysis

“…Not all patients had total thyroidectomy or information missing Tubiana et al, 1985;Harvey et al, 1990;Schlumberger et al, 1991; Jadvar et al, 1998 Not all patients had radioiodine ablation or information missing Shlossberg et al, 1979;Shah et al, 1981;Echenique et al, 1982;Tubiana et al, 1985;Black et al, 1987;Schlumberger et al, 1988;Brendel et al, 1990;Black & Sheppard, 1991;Ruiz-Garcia et al, 1991;Dadparvar et al, 1993; Ladenson et al, 1997;Ruter et al, 1998; Ladenson, 2000;Ng et al, 2000;Sisson et al, 2000;Vitale et al, 2002 Tg cut-off values not indicated Dadparvar et al, 1993; Bejarano et al, 2000; Ladenson, 2000 Criteria for tumour missing Ng Tang Fui et al, 1979;Eber et al, 1980; Bednar et al, 1983;Schlumberger et al, 1988;Rubello et al, 1990;Grunwald et al, 1997; Ladenson et al, 1997;Roelants et al, 1997;Lin et al, 1998;Almeida-Filho et al, 2000;Fugazzola et al, 2002 Patients with Tg antibodies not excluded or information missing Bednar et al, 1983;Feldt-Rasmussen et al, 1983;Edmonds & Willis, 1988;Schlumberger et al, 1991;Meier et al, 1994;Feine et al, 1996;Roelants et al, 1997;Ruter et al, 1998;Grunwald et al, 1999;Seabold et al, 1999;de Klerk et al, 2000;Ng et al, 2000;Rubello et al, 2000;…”