Diagnostic utility of high-sensitive troponin T in patients with acute coronary syndrome

Abstract

Cardiovascular diseases are the first cause of death in the world. Early detection of coronary pathologies contributes to the prevention of acute coronary events. High-sensitive troponin T is a valuable biomarker for diagnosing and assessing these patients. A retrospective cross-sectional study was performed from January 2018 to December 2020 at Hospicor-Manta. We included 571 patients who attended the Intensive Care Unit and had at least one high-sensitive troponin T determination with symptoms in the first 6 hours. Analyzing from the upper reference limit (99th percentile, allows understanding and interpreting data from the values below which a certain percentage is found for cardiac troponins. Elderly male patients tended to suffer acute coronary syndrome (p<0.05). The most frequent comorbidities were: arterial hypertension, dyslipidemia and diabetes (p< 0.05). There was evidence of the correlation between high-sensitive troponin T values and electrocardiographic signs of acute coronary syndrome (p<0.05). There was a moderate correlation between high-sensitive troponin T analysis and acute coronary syndrome (p< 0.05). Keywords: Cardiovascular diseases, acute coronary syndrome, high-sensitive troponin T.