Diagnostic Value of Echocardiography Combined with Serum h-FABP and cTnI in Myocardial Infarction and Its Evaluation Value in Left Ventricular Function

Abstract

Objective. To explore the value of color Doppler echocardiography (CDE) combined with serum heart-type fatty acid-binding protein (h-FABP) and cardiac troponin I (cTnI) in the diagnosis of myocardial infarction and its evaluation value in left ventricular function. Methods. A total of 44 patients with myocardial infarction who were treated in Cangzhou Central Hospital from October 2018 to February 2020 were included in the observation group, and 45 healthy subjects were included in the control group. The serum h-FABP and cTnI levels of the two groups were compared and analyzed. The coincidence rate of echocardiography plus serum h-FABP and cTnI for single diagnosis and combined diagnosis was analyzed. The left ventricular function indexes of patients with myocardial infarction in different cardiac function grades were compared, including left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), left ventricular end-systolic volume (LVESV), left ventricular end-diastolic volume (LVEDV), stroke volume (SV), cardiac index (CI), and the ratio of peak velocity blood flow from left ventricular relaxation in early diastole to peak velocity flow in late diastole (E/A). The value of echocardiography combined with serum h-FABP and cTnI in the left ventricular function in patients with myocardial infarction was analyzed. Results. The levels of serum h-FABP and cTnI in the observation group were significantly higher than those in the control group ( P < 0.05 ). CDE plus serum h-FABP and cTnI was associated with significantly higher sensitivity, specificity, and accuracy in diagnosing myocardial infarction versus single detection ( P < 0.05 ). The LVEDV, SV, and CI parameters were similar in patients with different cardiac function grades ( P > 0.05 ). Compared with cardiac function grades I and II, the level of LVEF in patients with myocardial infarction in grades III and IV of cardiac function decreased, while the levels of LVEDD, LVESD, LVESV, and E/A increased ( P < 0.05 ). The levels of serum h-FABP and cTnI in patients with myocardial infarction increased with the increase of cardiac function grades ( P < 0.05 ). Conclusion. Patients with myocardial infarction show high levels of h-FABP and cTnI, and CDE plus the detection of serum h-FABP and cTnI levels can significantly improve the detection accuracy and effectively evaluate the left ventricular function of patients with myocardial infarction, with a certain predictive value for cardiac function grading in myocardial infarction.

Hsp72-Based Effect and Mechanism of Microwave Radiation-Induced Cardiac Injury in Rats

“…Therefore, we developed a thermal effect model by extending the irradiation time in this study. In terms of index selection, we selected the changes in the levels of myocardial enzymes (CK-MB and HBDH) [ 8 ] and myocardial injury markers (H-FABP, cTnT, and NT-pro BNP) [ 9 , 10 ]. The reason behind our selection is that they are not only more closely related to clinical manifestations but are also more sensitive to myocardial injury than traditional myocardial enzymes such as AST.…”

Positive Effect of a Pea–Clam Two-Peptide Composite on Hypertension and Organ Protection in Spontaneously Hypertensive Rats

“…The heart index also supported our results, demonstrating that both pea peptides and the two-peptide composite can reduce hypertensive heart disease, and the effect of the two-peptide composite is more obvious. However, there are other biomarkers for cardiomyocyte injury and heart function, such as heart-type fatty acid binding protein (HFABP) and left ventricular ejection fraction (LVEF) [ 51 , 52 ]. Therefore, further study could be needed to explore the two-peptide composite’s effect on heart function.…”

Retracted: Diagnostic Value of Echocardiography Combined with Serum h‐FABP and cTnI in Myocardial Infarction and Its Evaluation Value in Left Ventricular Function

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”

“…Tis article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. Tis investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”