Diagnostic value of fine needle aspiration biopsy in parotid gland neoplasm

Abstract

<p class="abstract"><strong><span lang="EN-US">Background: </span></strong>The value of fine needle aspiration biopsy (FNAB) in the diagnosis of parotid masses remains unclear, considering current literature. The surgical procedure is not planned according to the FNAB results by the majority of the otorhinolaryngologists. Objectives of the study was to compare the results of FNAB and histopathological results in diagnosing malignancy and benign lesions of parotid gland and to determine the sensitivity, specificity and accuracy of FNAB.</p><p class="abstract"><strong><span lang="EN-US">Methods:</span></strong><span lang="EN-US"> It is a retrospective clinical chart review study. </span>In total, 61 patients (28 females and 33 males; average age, 46.31±15.79 years; age range: 12-82 years) with parotid gland masses who underwent preoperative FNAB were included in this study. All patients underwent FNAB under ultrasound guidance following clinical examination. Histopathological results of the surgical specimens and preoperative results of FNAB were compared and, the sensitivity, specify, positive predictive value (PPV), negative predictive value (NPV), the diagnostic accuracy of FNAB was calculated. A P-value <0.05 was considered to reflect statistical significance. </p><p class="abstract"><strong><span lang="EN-US">Results: </span></strong>The specificity of FNAB was 100% and its sensitivity was 57.2%. Accuracy for benign lesion was 91.4%, accuracy for a malignancy was 42.8% and overall diagnostic accuracy was 92.0%, respectively. PPV for benign lesion was 91.4% and the NPV was 100%, respectively. PPV for malignancy was 100% and the NPV was 91.4%, respectively.</p><p class="abstract"><strong><span lang="EN-US">Conclusions: </span></strong><span lang="EN-US">We suggest that FNAB is a valid, safe, easy-to-use method for identifying of parotid gland neoplasms. We recommend FNAB for all potential surgical patients. In our opinion, good collaboration between the Otorhinolaryngologist and the pathologist provides the best results.</span></p>

Study of the Cytomorphology of Salivary Gland Lesions Using the Milan System of Reporting in a Tertiary Care Hospital

“…Similar distributions of the tumor were noted in various studies. 9,14,16 The present study demonstrated sensitivity of 78.57% and specificity as 96.96%. The positive and negative predictive values were found to be 91.60% and 91.40% respectively.…”

“…The main reason for these false negative results may be sampling errors, observational errors, underassessment of low-grade tumors due to their bland cytological features. 9 In the current study, there were 3 false negative cases which are listed above.…”

“…It is a safe, easy to perform, well tolerated, relatively painless technique associated with minimal complications. 9 Our study aims to highlight the role of this procedure in our setup to diagnose salivary gland lesions, with an effort to streamline the management of salivary gland lesions using the classification based on the MILAN system for reporting salivary gland cytopathology, which is a relatively new concept. The objective of this classification system is to create a uniform reporting system that will assist in the effective communication of the results between the pathologists and the clinicians as well as for data evaluation and comparison between institutions.…”

Our Clinical Experiences in Parotid Masses: The Relationship Between the Size of Parotid Masses and the Results of Fine Needle Aspiration Biopsy

“…Tükürük bezi tümörleri, baş boyun tümörlerinin sadece %2-3 ' ünü oluşturmaktadır (2). Bu tümörler, tükürük bezlerinin bulunduğu her alanda görülebilmesine rağmen, en sık olarak parotis bezinde görülmektedir (3). Literatürde, tanımlanmış çok sayıda histopatolojik tükürük bezi tümörü bulunmaktadır.…”

“…-4 cm arasında olanlar için bu oranlar sırasıyla %50, %100, %100, % 80 ve %83.3 idi. Kitle boyutu 4 cm 'den büyük olanlar için bu oranlar sırasıyla %80, %100, %100, %50 ve %83 3. idi.…”