Diagnostic value of lung ultrasound in evaluating the severity of neonatal respiratory distress syndrome

Pang, Houqing; Zhang, Bo; Zang, Jing; Qiu, Li

doi:10.1016/j.ejrad.2019.05.004

Cited by 48 publications

(67 citation statements)

References 26 publications

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“…True consolidations are hypoechogenic triangular-shaped changes with visible air bronchogram, while uid alveologram is a subpleural accumulation of exudative uid, which mixed with air, ful lls the alveoli. Fluid alveologram can be observed in severe RDS [10] and, as a rule, is not seen in the rst day of life but rather in the following days. Since the study covered the entire rst month of life of premature babies, it seems appropriate to classify this type of change separately.…”

Section: Discussionmentioning

confidence: 99%

“…To date, several studies have been published assessing the clinical usefulness of lung ultrasound in newborns with respiratory disorders [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. These works focused mainly on preterm infants with RDS and transient tachypnea of the newborn (TTN); in both cases, LUS was performed primarily on the rst day of life.…”

Section: Discussionmentioning

confidence: 99%

“…In studies where lung ultrasound images were quanti ed, four-grade scales were mainly used (a score of 0-1-2-3) [1,3,5,6,[8][9][10][11]. In our work, we proposed a ve-grade scale (a score of 0-1-2-3-4), de ning an additional category of "white lung with uid alveologram".…”

Section: Discussionmentioning

confidence: 99%

“…We abandoned the division of pulmonary elds into upper and lower sections. Previously, Pang et al [10] expanded the assessment scales by including posterior pulmonary elds, dividing each of the studied lung areas into the upper and lower parts while maintaining a four-grade scale. This type of division used also by Raimondi et al [11] is adopted from adult studies, where due to the chest size, it seems expedient.…”

Section: Discussionmentioning

confidence: 99%

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A Modified Lung Ultrasound Score for Assessing Oxygenation Status and Predicting the Need for Invasive Ventilation in Preterm Neonates with RDS

Szymański¹,

Kruczek²,

Hożejowski³

et al. 2020

Preprint

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PurposeWe propose a modified lung ultrasound score (LUS) in neonates with respiratory distress syndrome (RDS), which includes posterior instead of lateral lung fields, and a 5-grade rating scale instead of a 4-grade rating scale. The LUS was evaluated for validity, interrater agreement and prognostic power in relation to the need for respiratory support on day of life (DOL) 3. The hypothesis of the dominant weight of posterior scans in the LUS was also verified.Materials and methodsA total of 647 serial lung scans were performed in 70 preterm infants <32 weeks gestation and birth weight <1500 g. Assessments were performed within 24 hours of birth (LUS0) and on days 2, 3, 5, 7, 10, 14, 21 and 28. LUS was correlated to oxygen saturation over fraction of inspired oxygen (SpO2/FiO2) and mode of respiratory support. Probabilities of the need for respiratory support on DOL 3 were assessed with ordinal logistic regression.ResultsThe LUS correlated significantly with SpO2/FiO2 (Spearman rho = -0.635; p<0.0001) and had excellent interrater agreement (Cronbach’s alpha = 0.99). Posterior fields had dominant weight over the anterior fields (ls mean [confidence level]) 4.0 [3.8–4.1] vs 2.2 [2.0–2.4]; p<0.0001. Significant predictors of ventilation requirements on DOL 3 were LUS0 (p<0.016) and birth weight (BW) (p<0.0001); invasive ventilation was the most likely option with LUS0 ≥7 (BW 900 g), ≥10 (BW 1050 g) and ≥15 (BW 1280 g).ConclusionPostbirth LUS predicts the need for mechanical ventilation on DOL 3. Posterior fields play a dominant role in sonographic assessment of lungs in neonatal RDS.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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A Modified Lung Ultrasound Score for Assessing Oxygenation Status and Predicting the Need for Invasive Ventilation in Preterm Neonates with RDS

Szymański¹,

Kruczek²,

Hożejowski³

et al. 2020

Preprint

View full text Add to dashboard Cite

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“…This modality has its own potential adverse effects including thermal and mechanical tissue damage [27,29]. Recently, lung ultrasound has been widely used as an accurate diagnostic tool according to published clinical studies [4,7,16,[30][31][32][33][34]. Lack of normal air-filled levels and presence of fluid level is a diagnostic clue for NRDS.…”

Section: Ultrasoundmentioning

confidence: 99%

Neonatal Respiratory Distress Syndrome: Things to Consider and Ways to Manage

Najafian¹,

Khosravi²

2020

Update on Critical Issues on Infant and Neonatal Care

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Involving more commonly the premature (less than 37 weeks of gestational age) infants, neonatal respiratory distress syndrome is an important clinical syndrome responsible for a high rate of mortality and morbidity. The main progress in respiratory distress syndrome (RDS) management is attributable to prescription of surfactant for fastening pulmonary maturation. Respiratory protection, such as mechanical ventilation and nasal continuous positive airway pressure, and surfactant are building blocks of disease treatment. In this chapter, we are going to have a rapid review on epidemiology, diagnosis and treatments of RDS.

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Lung Ultrasound in the Evaluation of Neonatal Respiratory Distress Syndrome

Hua

Wang

Wei

et al. 2022

J of Ultrasound Medicine

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Objective The purpose of this study is to examine the impact of bedside lung ultrasound (LUS) and LUS scores in the evaluating and grading of neonatal respiratory distress syndrome (NRDS). Methods We performed a prospective study on 80 children with suspected NRDS. Infants with a PaO2‐to‐FiO2 ratio of <200, 200–300, and >300 mmHg were categorized as the “severe‐NRDS group,” “mild‐NRDS group,” and “non‐NRDS group,” respectively. Left and right lungs were divided into six areas, respectively. For each lung area, a 0‐ to 3‐point score was given. Results The most common ultrasonic signs of NRDS include bilateral coalescent B‐lines, thickened pleural line, and white lung without spared areas. Moreover, different LUS scores among non‐NRDS, mild‐NRDS, and severe‐NRDS groups were identified (6.00 ± 4.033, 25.82 ± 3.778 and 27.90 ± 4.071, respectively; P < .05). When the cutoff value of LUS score was selected as 13 for the differentiation of non‐NRDS from NRDS, the sensitivity and specificity were 96.9% and 93.3%, respectively, and the area under the curve (AUC) of receiver operating characteristics (ROC) was 0.938 (95% confidence interval [CI], 0.84–1.00). With a cutoff value of 26.5 for the differentiation between mild‐ and severe‐ARDS, the AUC of ROC curve of the LUS score was 0.707 (95% CI, 0.58–0.83). Similar results were revealed as those with chest X‐ray. Conclusion This study showed that LUS and LUS scores complement each other, and are highly reliable and efficient in bedside radiological diagnostic investigations in newborns with NRDS.

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Diagnostic value of lung ultrasound in evaluating the severity of neonatal respiratory distress syndrome

Cited by 48 publications

References 26 publications

A Modified Lung Ultrasound Score for Assessing Oxygenation Status and Predicting the Need for Invasive Ventilation in Preterm Neonates with RDS

A Modified Lung Ultrasound Score for Assessing Oxygenation Status and Predicting the Need for Invasive Ventilation in Preterm Neonates with RDS

Neonatal Respiratory Distress Syndrome: Things to Consider and Ways to Manage

Lung Ultrasound in the Evaluation of Neonatal Respiratory Distress Syndrome

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