Diagnostic value of pipelle endometrial sampling in comparison with dilatation and curettage among patients with abnormal uterine bleeding

Alliratnam, A S; Priya, S. Senthil; Shankar, R. Ravi

doi:10.18203/2320-1770.ijrcog20160600

Cited by 5 publications

(1 citation statement)

References 5 publications

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“…This is similar to a study by Mathew et al 16 and Sanam M et al 22 05 inadequate samples in our study were in the post-menopausal age group, they went on to have diagnostic dilation and curettage which showed atrophic endometrium on histopathology. This is comparable to a study done by Asif et al 21 where inadequate samples were 04%. Pipelle Sampling is an effective tool in diagnosing endometrial pathology when combined with proper history, examination, and ultrasound.…”

Section: Resultssupporting

confidence: 90%

Assessing the Efficacy of Pipelle Sampling as Outpatient Diagnostic Test in a Tertiary Care Hospital-Rawalpindi, 2020

Noor

Anwar²,

Akbar³

et al. 2020

JRMC

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ABSTRACT Objective: To assess the effectiveness and enlist clinical factors, which may affect effectiveness of Pipelle sampling in diagnosing endometrial pathology in patients with abnormal uterine bleeding and Post-menopausal Bleeding. Study Design: ‘Analytical Cross-Sectional’ study. Place and duration: Gynecology Department at Combined Military Hospital Rawalpindi, in collaboration with Histo-Pathology Department, of six months duration i.e. from 1st December 2019 to 31st May 2020. Patients and methods: 100 female patients of outpatient department with presenting complaints of either abnormal or post-menopausal bleeding were included in the study in the specified time frame. After informed written consent, Pipelle endometrial sampling was done on outpatient basis, and by consecutive sampling technique using lottery method, sample was sent for histopathological evaluation. Evaluated factors studied were: indications for the procedure, age, parity, age of menarche. Results: Of the total patients evaluated, 91% (n=100) were non-malignant, while 4% (n=100) were malignant. Inadequate tissue was obtained in 5% samples. Most common histopathological findings among reproductive age group were Proliferative and Secretory phase endometrium 64% (n=100). While in Post-menopausal age group 4% (n=100) were Endometrial carcinoma on histopathology. Inadequate tissue samples 5% (n=100) were noted among the Post-menopausal group. 6% samples showed endometrial hyperplasia. Pipelle Endometrial Sampling had sensitivity and specificity, in diagnosing the endometrial pathologies is summarized in Table 3. Conclusion: Pipelle Endometrial Sampling is an effective, safe, simple and acceptable procedure for diagnosing endometrial pathology. It is cost effective requiring no anesthesia with high sensitivity and specificity for detecting endometrial pathology.

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Section: Resultssupporting

confidence: 90%

Assessing the Efficacy of Pipelle Sampling as Outpatient Diagnostic Test in a Tertiary Care Hospital-Rawalpindi, 2020

Noor

Anwar²,

Akbar³

et al. 2020

JRMC

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A diagnostic value of Pipelle endometrial sampling in comparison with dilatation and curettage among patients with abnormal uterine bleeding

Desai,

Vaijinath,

Vishwaradhya

et al. 2024

IJOGR

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Pipelle aspirator and Dilatation and Curettage (D&C) commonly used to obtain the endometrial sample in patients of abnormal uterine bleed (AUB). This study was conducted to determine the reliability of pipelle device in acquiring an adequate representative endometrial sample when compared to D&C. This prospective comparative study was conducted in a tertiary care hospital in India. One hundred cases of AUB attending the outpatient clinic due to endometrial causes (thick endometrium≥ 12mm in the reproductive and ≥ 4mm in postmenopausal age) were included for the study. Exclusion criteria: AUB due to proven endometrial polyp, coagulopathy. The endometrial sample was taken by the Pipelle device and D&C on the same day. A pathologist, who was blinded to the methods of sample collection, reported the same. The histopathology reports of the Pipelle were compared with that of the D&C sample and the D&C report was considered the gold standard.A 2×2 table of true positive (TP) true negative (TN), False positive (FP) and False negative (FN) was prepared and used for calculating sensitivity, specificity of the pipelle method when compared to D&C. The pathologists classified 96% of the pipelle and 100% of D&C samples as adequate. Higher age, postmenopausal status and thinner endometrium were associated with inadequate sample in pipelle. Pipelle sample had 100% sensitivity and specificity for detecting endometrial carcinoma, hyperplasia, with or without atypia. Pipelle method could not identify any of the polyp, diagnosed with D&C. Pipelle had good correlation for detecting proliferative, secretory endometrium and endometritis. Pipelle device provides adequate sample for histopatholgical examination 96% of the patients. Pipelle sample is 100% sensitive and specific for diagnosing endometrial carcinoma, endometrial hyperplasia with or without atypia. Pipelle method is ineffective for diagnosing polyp.

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Comparison of Diagnostic Efficacy of Pipelle Endometrial Biopsy with Dilatation and Curettage in Patients with Abnormal Uterine Bleeding

Patankar¹,

Nitnaware²

2020

jebmh

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Diagnostic value of pipelle endometrial sampling in comparison with dilatation and curettage among patients with abnormal uterine bleeding

Cited by 5 publications

References 5 publications

Assessing the Efficacy of Pipelle Sampling as Outpatient Diagnostic Test in a Tertiary Care Hospital-Rawalpindi, 2020

Assessing the Efficacy of Pipelle Sampling as Outpatient Diagnostic Test in a Tertiary Care Hospital-Rawalpindi, 2020

A diagnostic value of Pipelle endometrial sampling in comparison with dilatation and curettage among patients with abnormal uterine bleeding

Comparison of Diagnostic Efficacy of Pipelle Endometrial Biopsy with Dilatation and Curettage in Patients with Abnormal Uterine Bleeding

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