Diagnostic value of rapid on-site evaluation during transbronchial biopsy for peripheral lung cancer

Wang, Juan; Zhao, Yaping; Chen, Qianqian; Zhang, Peng; Xie, Wei; Feng, Jing; Cao, Jie

doi:10.1093/jjco/hyz025

Cited by 13 publications

(15 citation statements)

References 24 publications

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“…ROSE significantly improved the diagnostic yield of peripheral lung cancer. The diagnostic yield in the ROSE group was 12.2% higher than that in the non‐ROSE group . The researchers suggested that ROSE can reduce complications and re‐examination of bronchoscopy.…”

Section: Discussionmentioning

confidence: 99%

“…In this study, there were no differences in the accuracy of ROSE among EBUS‐TBNA and EBUS‐GS. Reports on the benefits of ROSE in EBUS‐GS presented advantages such as reduced procedure times and increased diagnostic yield . ROSE significantly improved the diagnostic yield of peripheral lung cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Reports on the benefits of ROSE in EBUS-GS presented advantages such as reduced procedure times and increased diagnostic yield. [15][16][17]23,24 ROSE significantly improved the diagnostic yield of peripheral lung cancer. The diagnostic yield in the ROSE group was 12.2% higher than that in the non-ROSE group.…”

Section: Ta B L E 1 Baseline Features Of the Patientsmentioning

confidence: 99%

“…The diagnostic yield in the ROSE group was 12.2% higher than that in the non-ROSE group. 23 The researchers suggested that ROSE can reduce complications and re-examination of bronchoscopy. Izumo et al showed that ROSE during EBUS-GS had high sensitivity, whereas its specificity and overall diagnostic efficacy were lower than those of ROSE during EBUS-TBNA.…”

Section: Ta B L E 1 Baseline Features Of the Patientsmentioning

confidence: 99%

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Feasibility of rapid on‐site cytological evaluation of lung cancer by a trained pulmonologist during bronchoscopy examination

et al. 2019

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Objective Rapid on‐site cytological evaluation (ROSE) in bronchoscopy is a useful ancillary technique. ROSE is usually performed by a cytopathologist or cytotechnologist. However, because of staff shortages and reduced availability, ROSE cannot be performed in every hospital. We aimed to evaluate the accuracy of ROSE when performed by a trained pulmonologist, comparing the diagnosis results with the final diagnosis of cytopathologists. Methods We performed a retrospective cohort study on 125 patients who underwent bronchoscopy with endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) and endobronchial ultrasonography with a guide sheath (EBUS‐GS) for peripheral pulmonary lesions by conventional bronchoscopy at Sapporo Medical University Hospital between March 2012 and September 2018. ROSE was performed by a pulmonologist who was trained by a cytotechnologist for a total of 1 month. DiffQuik® staining for ROSE was used to prepare cytology slides. The results of ROSE were compared with the final diagnosis obtained using Papanicolaou staining by cytopathologists. Results In all procedures, the sensitivity, specificity and diagnostic accuracy of ROSE were 88.5%, 83.0% and 86.4%, respectively. There was no significant difference in the sensitivity, specificity, positive predictive value, negative predictive value or accuracy between EBUS‐TBNA and EBUS‐GS. Conclusions ROSE of lung cancer by a trained pulmonologist can be highly accurate and deemed as feasible and useful for not only EBUS‐TBNA but also EBUS‐GS.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Ta B L E 1 Baseline Features Of the Patientsmentioning

confidence: 99%

Section: Ta B L E 1 Baseline Features Of the Patientsmentioning

confidence: 99%

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Feasibility of rapid on‐site cytological evaluation of lung cancer by a trained pulmonologist during bronchoscopy examination

et al. 2019

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“…As a "real-time accompany technique", rapid on-site evaluation(ROSE) can be performed in various interventional procedure, including puncture, biopsy, brushing and etc [3][4][5]. It's recommended to use ROSE from the point of reducing complications and enhancing the diagnostic yield [6]. However, the diagnostic value of ROSE in infectious diseases is ignored.…”

Section: Introductionmentioning

confidence: 99%

Rapid On-Site Evaluation, As a Diagnostic Method for PCP in a Patient with Nephrotic Syndrome

Weng

Chen

et al. 2021

Preprint

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Background: Pneumocystis jirovecii pneumonia (PCP) is a common illness of the patients receiving long-term immunosuppressive treatment for which therapy is currently available. Early and prompt diagnosis of this pulmonary infection is a matter of great practical importance. Clinical presentation and radiology are not enough to confirm a diagnosis of PCP. Microscopic examination is available.Case presentation: Here we report a 63-year-old man with nephrotic syndrome,who was transferred to ICU due to unexplained aggravation of infection. The cause of pulmonary infection was identified by Rapid on-site evaluation (ROSE) finally and targeted treatment was given.Conclusions: ROSE can be a diagnostic approach for PCP, which is suitable for clinicians.

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Diagnostic performance of rapid on‐site evaluation during bronchoscopy for lung cancer: A comprehensive meta‐analysis

Chen,

Lu,

Chang

et al. 2024

Cancer Cytopathology

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BackgroundLung cancer is the leading cause of cancer‐related mortality worldwide. Screening high‐risk populations for lung cancer with low‐dose computed tomography (LDCT) reduces lung cancer mortality. Bronchoscopy is a diagnostic procedure used to monitor patients suspected of having lung cancer after LDCT. Rapid on‐site evaluation (ROSE) can improve the diagnostic accuracy of endobronchial ultrasound–guided transbronchial needle aspiration (EBUS‐TBNA), although its diagnostic value remains unclear. In this meta‐analysis, the authors evaluated the diagnostic accuracy of ROSE during bronchoscopy.MethodsThe PubMed, Embase, and Cochrane Library databases were searched for studies evaluating the diagnostic accuracy of ROSE for lung cancer during bronchoscopy. Studies evaluating the performance of ROSE and articles providing sufficient data for constructing a 2 × 2 table on a per‐lesion basis were included. A meta‐analysis was conducted using a bivariate random‐effects model.ResultsIn total, 32 studies involving 8243 lung lesions were included with a pooled sensitivity of 91.8% and a pooled specificity of 94.9%. Subgroup analysis of 12 studies involving 2929 specimens from patients who underwent computed tomography revealed a pooled sensitivity of 93.8% and a pooled specificity of 96%. Further subgroup analysis of seven studies on the diagnostic outcomes of ROSE for intrathoracic or mediastinal lymph nodes through EBUS‐TBNA for lung cancer staging revealed a pooled sensitivity of 90.1% and a pooled specificity of 96.9%.ConclusionsROSE exhibited high sensitivity and specificity for diagnosing lung cancer during bronchoscopy. It also exhibited high sensitivity in detecting lung cancer in patients undergoing LDCT and higher specificity for nodal staging with EBUS‐TBNA.

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Diagnostic value of rapid on-site evaluation during transbronchial biopsy for peripheral lung cancer

Cited by 13 publications

References 24 publications

Feasibility of rapid on‐site cytological evaluation of lung cancer by a trained pulmonologist during bronchoscopy examination

Feasibility of rapid on‐site cytological evaluation of lung cancer by a trained pulmonologist during bronchoscopy examination

Rapid On-Site Evaluation, As a Diagnostic Method for PCP in a Patient with Nephrotic Syndrome

Diagnostic performance of rapid on‐site evaluation during bronchoscopy for lung cancer: A comprehensive meta‐analysis

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