Diagnostic value of Tg and TgAb for metastasis following ablation in patients with differentiated thyroid carcinoma coexistent with Hashimoto thyroiditis

Chai, Hong; Zhu, Zhao-Jin; Chen, Zequan; Yu, Yongli

doi:10.3109/07435800.2015.1010210

Cited by 4 publications

(1 citation statement)

References 17 publications

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“…Tg is a glycoprotein that is mainly secreted by the thyroid follicular epithelium, and its expression in the healthy human body is low. 16 , 17 However, patients with thyroid cancer develop inflammatory responses due to thyroid tissue damage, which may induce the activation of thyroid epithelial cells, 18 thereby causing them to release more Tg. 19 Therefore, Tg is highly expressed in patients with thyroid cancer.…”

Section: Discussionmentioning

confidence: 99%

Differential diagnostic value of the ResNet50, random forest, and DS ensemble models for papillary thyroid carcinoma and other thyroid nodules

et al. 2022

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Objective To explore the differential diagnostic efficiency of the residual network (ResNet)50, random forest (RF), and DS ensemble models for papillary thyroid carcinoma (PTC) and other pathological types of thyroid nodules. Methods This study retrospectively analyzed 559 patients with thyroid nodules and collected thyroid pathological images and auxiliary examination results (laboratory and ultrasound results) to construct datasets. The pathological image dataset was used to train a ResNet50 model, the text dataset was used to train a random forest (RF) model, and a DS ensemble model was constructed from the results of the two models. The differential diagnostic values of the three models for PTC and other types of thyroid nodules were then compared. Results The DS ensemble model had the highest sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (85.87%, 97.18%, 93.77%, and 0.982, respectively). Conclusions Compared with Resnet50 and the RF models trained only on imaging data or text information, respectively, the DS ensemble model showed better diagnostic value for PTC.

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Section: Discussionmentioning

confidence: 99%

Differential diagnostic value of the ResNet50, random forest, and DS ensemble models for papillary thyroid carcinoma and other thyroid nodules

et al. 2022

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Metastatic differentiated thyroid cancer with negative serum stimulated Tg but positive post-therapeutic 131I-SPECT/CT scintigraphy: a single-center retrospective study

Yan

et al. 2023

Endocrine

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The Clinical Significance of Monitoring the Changes of TGAb Level in Patients with Differentiated Thyroid Cancer When Serum Tg Value Is False Negative

袁¹

2022

ACM

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Diagnostic value of Tg and TgAb for metastasis following ablation in patients with differentiated thyroid carcinoma coexistent with Hashimoto thyroiditis

Abstract: In DTC coexistent with HT patients, the optimal cutoff value correlated with metastasis in Tg and TgAb was 1.48 µg/L and 45 kIU/L, respectively.

Cited by 4 publications

References 17 publications

Differential diagnostic value of the ResNet50, random forest, and DS ensemble models for papillary thyroid carcinoma and other thyroid nodules

Differential diagnostic value of the ResNet50, random forest, and DS ensemble models for papillary thyroid carcinoma and other thyroid nodules

Metastatic differentiated thyroid cancer with negative serum stimulated Tg but positive post-therapeutic 131I-SPECT/CT scintigraphy: a single-center retrospective study

The Clinical Significance of Monitoring the Changes of TGAb Level in Patients with Differentiated Thyroid Cancer When Serum Tg Value Is False Negative

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