Diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy in Sri Lanka

Jayarajah, Umesh; Vidanapathirana, S.; Mahadewa, Shinthujaa; Wijayagunawardena, Saranga; Senthan, Velayuthan; Edirisinghe, Kapila; Ambegoda, Madura; Abeygunasekera, Anuruddha M

doi:10.4038/cmj.v66i4.9506

Ceylon Med. J.

2021

DOI: 10.4038/cmj.v66i4.9506

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Diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy in Sri Lanka

Umesh Jayarajah¹,

S. Vidanapathirana

Shinthujaa Mahadewa³

et al.

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2024

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Research on the mean maximum Young’s modulus value as a new diagnostic parameter for prostate cancer

Duan,

Liu,

et al. 2024

Sci Rep

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Ultrasound-based shear wave elastography (SWE) can non-invasively assess prostate tissue stiffness for the diagnosis of prostate cancer (PCa). So far, there is no widely recognized standard for the detection process and calculation method of Young’s modulus value in transrectal SWE ultrasound imaging (TSWEUI). In our study, the mean maximum Young’s modulus value (m-Emax) of the maximum cross-section of prostate is obtained by calculating the mean of 12 measured Emax in the four quadrants. This retrospective study included 209 suspected malignant prostate disease patients with pathological results in our hospital. Among the 209 patients, 75 patients completed TSWEUI, and 63 of the 75 patients completed magnetic resonance imaging (MRI). The area under the receiver operating characteristic (ROC) curve (AUC) of 75 patients for m-Emax was 0.754. The prostate volume, prostate-specific antigen, and m-Emax were used to develop a nomogram (AUC = 0.868). The nomogram could effectively predict the probability of PCa, thereby reducing the needle biopsy rate for diagnosing PCa. The AUC of 63 patients was not statistically different between m-Emax (AUC = 0.717) and MRI (AUC = 0.787) ( P = 0.361). These indicate that m-Emax can be used as an innovative parameter in TSWEUI to diagnosis PCa. TSWEUI is more cost-effective than MRI in diagnosing PCa.

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Research on the mean maximum Young’s modulus value as a new diagnostic parameter for prostate cancer

Duan,

Liu,

et al. 2024

Sci Rep

View full text Add to dashboard Cite

show abstract

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Diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy in Sri Lanka

Cited by 1 publication

References 12 publications

Research on the mean maximum Young’s modulus value as a new diagnostic parameter for prostate cancer

Research on the mean maximum Young’s modulus value as a new diagnostic parameter for prostate cancer

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