Introduction: Getting old is a natural process. The quality of life and independency lived during this stage depend not only on the genetic structure, but also on what is done throughout the entire life. Objective: To explore the relationship among the levels of quality of life, dependency, and self-care in the elder adult. Methods: This is a transversal, descriptive, and correlational study. One hundred and sixteen elder adults who attended consultation visits at a health unit were interviewed. The variables studied were: dependency, self-care, and quality of life. The Barthel scale, the Self-Care Capacities Scale, and the SF-36 Quality of Life Questionnaire were used. The Pearson and Spearman correlations were calculated. This project was reviewed and approved by a Research Committee.Results: Fifty four point three percent of the participants were female. The 80.2% of the elder adults interviewed showed independence to perform their daily life activities, while the rest (19.8%) showed a mild level of dependency. In relation to the self-care activities, 22.4% showed a good capacity, while 76.6% showed a very good capacity. In relation to their perception of quality of life, in the physical dimension, 24% of the participants considered their health as good, while 56% consider it as more or less good. In the correlation tests, a minimal relationship was found between the variables of self-care and dependency, also, a low relationship was found between the self-care and the school levels. A positive correlation was found between dependency and quality of life, and also between quality of life and age, though their values were low.