The relevance of the problem of HC is also related to the issues of etiology, pathogenesis, diagnosis, conservative and surgical treatment. To date, none of the many proposed methods of conservative and surgical treatment has one hundred percent effectiveness. According to literature data, there are no official epidemiological data at the federal level on the prevalence of chronic constipation in Russia. On the territory of the Russian Federation, the diagnosis is made according to the leading clinical disease, syndrome and/or symptom corresponding to ICD 10 – K59.0 – constipation. Modern scientific evidence suggests that the detection of metabolic disorders, chronic constipation, and microbiota disorders in a patient should be regarded as clinical and pathogenetic links of a single pathological process.