Diagnostics of Oxidative Stress by Laser Optical-Acoustic Spectroscopy

Abstract

The results of the registration of oxidative stress volatile molecular markers (NOx, C2H6, and C5H12) in exhaled air by optical-acoustic spectroscopy are presented. Aerobic physical exercises were chosen as a method of oxidative stress activation. Three time points were studied: before exercises, immediately after exercises, and after 25 min rest. It was shown that there is a statistically significant increase in the studied markers concentrations in the exhaled air immediately after the exercises. After the rest, statistically significant differences are observed in relation to the initial state only for a part of these markers. This is most likely caused by different recovery of the subjects after the exercises and insufficient rest time. Thus, this instrumental approach is promising for non-invasive registration of markers of oxidative stress.

A novel Raman spectroscopic method for detecting traces of blood on an interfering substrate

“…Another approach to extract a certain component concentration from an IR absorption spectrum of a complex gas mixture was developed by us 40 , 41 . The approach starts from degenerating Eq.…”