Diallyl sulfide-induced attenuation of n-hexane-induced peripheral nerve impairment is associated with metabolic inhibition of n-hexane

Li, Xianjie; Yu, Ting; Wang, Shuo; Wang, Qiong; Li, Ming; Liu, Zhidan; Xie, Keqin

doi:10.1016/j.fct.2020.111167

Cited by 9 publications

(2 citation statements)

References 36 publications

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“…NH is a colorless organic compound that belongs to the straight-chain saturated hydrocarbon (1). It is considered a low-boiling chemical that is volatile at room temperature because of its boiling point of 69 • C and vapor pressure of 127.5 mmHg at 25 • C. It has the advantages of low price and good performance, and thus it is widely used in various production processes.…”

Section: Introductionmentioning

confidence: 99%

Application of multiple occupational health risk assessment models in the prediction of occupational health risks of n-Hexane in the air-conditioned closed workshop

Zhu¹,

Su²,

Wen³

et al. 2022

Front. Public Health

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Backgroundn-Hexane (NH) poisoning is a common occupational poisoning in the hardware and electronics industries. However, there is few research data on risk assessment of positions using NH in enclosed workshops. It is very important to assess the risk level of these positions and put forward effective measures and suggestions.MethodsThe information of selected companies and air samples were collected through on-site investigation, and data collation and sample testing were carried out according to the requirements of Chinese standards. The Control of Substances Hazardous to Health (COSHH) Essential, the EPA non-carcinogenic risk assessment model, the Singapore exposure index method and the Chinese semi-quantitative risk assessment models were used to assess the risks of NH.ResultsThe working hours of the exposure groups, printing groups and packing groups all exceeded 9 h per day, less than 30% of each similar exposure groups (SEG) was equipped with the local exhaust ventilation, and 11.1% of the cleaning group and 8.3% of the printing group had NH concentrations in the air that exceeded the Chinese occupational exposure limit (OEL). In the EPA non-carcinogenic risk assessment model, each SEG was evaluated at high risk. In the Chinese semi-quantitative risk assessment models, all of the work groups of exposure groups, 91.7% of the work groups of printing groups, 77.8% of the work groups of printing groups, and 57.1% of the work groups of printing groups were evaluated at unacceptable risk. More than 40.0% of the work groups of printing groups and cleaning groups and over 20.0% of the work groups of exposure groups and packing groups were evaluated at high risk in the Chinese semi-quantitative risk assessment models.ConclusionsThe Chinese exposure index method and the synthesis index method may have a stronger practicability. Some work groups that use NH in air-conditioned enclosed workshops in China, especially the cleaning groups, are still in a high-risk state. It is necessary to increase protective measures and strengthen occupational hygiene management to reduce risks.

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Section: Introductionmentioning

confidence: 99%

Application of multiple occupational health risk assessment models in the prediction of occupational health risks of n-Hexane in the air-conditioned closed workshop

Zhu¹,

Su²,

Wen³

et al. 2022

Front. Public Health

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“… Experimental design All sampling and analysis of n-hexane concentration were conducted according to previous studies [1] , [2] . Trial registration – Ethics – Value of the Protocol • N-Hexane, as a hydrophobic VOCs is widely used as a cleaning agent in textiles, furniture, leather products and as a solvent in oil and grease removal and oil extraction of vegetables [3 , 4] . • N-hexane due to its low bioavailability and low solubility in water is poorly removed in biological treatment systems [5] , [6] , [7] .…”

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confidence: 99%

Effect of photocatalytic pretreatment on the biodegradation of n-hexane vapours in a biofilter

et al. 2020

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Hydrophobic volatile organic compounds (VOCs) such as n-hexane are not completely biodegradable by a single biofilter. So, in the present study, a photoreactor system packed with scoria granules coated with TiO 2 , as a pretreatment unit, was used for increasing the removal efficiency of n-hexane by a biofilter during an operation period of 191 days. The inlet and outlet concentration of n-hexane was analyzed with a gas chromatography coupled with a flame ionization detector (GC/FID). The results indicated that the removal efficiency of the single biofilter with input concentrations of 0.18 – 1 g/m 3 at empty bed residence times (EBRTs) of 30, 60, and 120 s was 10.06%, 21.45%, and 46.8%, respectively. When the photoreactor was used as a pretreatment system, the removal efficiency of the combined system in corresponding EBRTs was improved to 39.79%, 63.08%, and 92.60%, respectively. The results proved that the combined system provided higher removal efficiencies than the single biofilter. Thus, the application of the photoreactor as a pretreatment step was much effective in increasing the removal efficiency of n-hexane from the polluted air by the biofilter.

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Exploring Hexane's impact: Toxicological insights, challenges, and forward-looking perspectives

Kumar,

Pandey

2025

Hazardous Chemicals

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Diallyl sulfide-induced attenuation of n-hexane-induced peripheral nerve impairment is associated with metabolic inhibition of n-hexane

Cited by 9 publications

References 36 publications

Application of multiple occupational health risk assessment models in the prediction of occupational health risks of n-Hexane in the air-conditioned closed workshop

Application of multiple occupational health risk assessment models in the prediction of occupational health risks of n-Hexane in the air-conditioned closed workshop

Effect of photocatalytic pretreatment on the biodegradation of n-hexane vapours in a biofilter

Exploring Hexane's impact: Toxicological insights, challenges, and forward-looking perspectives

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