DIALYSIS AMYLOIDOSIS WITH MASSIVE POPLITEAL DEPOSITION OF Β2-Microglobulin AMYLOID

Brancaccio, Diego; Gallieni, Maurizio; Padovese, P.; Anelli, Adriana; Coggi, Guido; Uslenghi, C

doi:10.1016/s0140-6736(88)92459-2

Cited by 22 publications

(11 citation statements)

References 4 publications

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“…The masses were associated with discomfort on sitting. Small nodules due to the infiltration of tendons with amyloid are a recognised feature of B2M amyloid and may be associated with triggering of fingers [7], There have been 2 case reports of popliteal masses due to B2M amyloid [8,9] and our case highlights the importance of palpation of the gluteal region in the assessment of patients with dialysis arthropathy. We have since discovered bilateral gluteal tumours in one more patient who has been on haemodialysis for 20 years, although no histological tis sue has yet been obtained.…”

Section: Discussionmentioning

confidence: 72%

Macroglossia and Amyloidoma of the Buttock: Evidence of Systemic Involvement in Dialysis Amyloid

Sethi

Hutchison

Cary

et al. 1990

Nephron

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A 48-year-old male on cuprophane haemodialysis for 18 years, with a history of dialysis arthropathy and recurrent carpal tunnel syndrome developed macroglossia and bilateral buttock tumoral masses. The tongue and buttock masses were biopsied. Histology of both biopsies showed amyloid deposits of the β₂-microglobulin (B2M) variety. Amyloidomas in the gluteal region and macroglossia have not been previously described in amyloid derived from B2M. These findings suggest that systemic B2M amyloidosis can have a similar tissue distribution to AL amyloidosis. This case also stresses the importance of inspection of the tongue, and palpation of the gluteal region for masses, in the assessment of patients with dialysis arthropathy.

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Section: Discussionmentioning

confidence: 72%

Macroglossia and Amyloidoma of the Buttock: Evidence of Systemic Involvement in Dialysis Amyloid

Sethi

Hutchison

Cary

et al. 1990

Nephron

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“…Laurent et al 16 reported an incidence of 30% in patients who were undergoing hemodialysis for 10 years, 50% for 15 years, and 100% for 20 years. The incidence of entrapment neuropathy in hemodialysis patients may be increased, not only by susceptibility to nerve compression as a result of uremia and amyloidosis but also by direct compression by a bursa 3,22 or inflammatory tissue. 15 In our cases, cubital tunnel syndrome had gradually worsened without an acute attack of neuritis.…”

Section: Discussionmentioning

confidence: 99%

Cubital tunnel syndrome caused by uremic tumoral calcinosis

Özalay

Cesur

Akpınar

et al. 2006

Journal of Shoulder and Elbow Surgery

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“…AP2M amyloidosis can also manifest in dialysis pa tients with subcutaneous tumorous deposits [63][64][65][66], while diffuse infiltration of the subcutaneous fat or skin are not usually present [ 18,33,67,68].…”

Section: Other Musculoskeletal Symptoms Caused By Aft ?M Amyloidosismentioning

confidence: 99%

Beta-2-Microglobulin-Associated Amyloidosis

Floege

Ehlerding²

1996

Nephron

129

111

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β₂-Microglobulin-associated amyloidosis has emerged as a major complication of long-term renal replacement therapy. The syndrome is confined to those patients on nontransplant modes of therapy. It does not occur in patients with a functioning renal transplant or, if already present, it does not progress any further in such patients. In the population of ESRD patients on dialysis, β₂-microglobulin-associated amyloidosis affects most patients treated for more than 15 years and is a cause of significant morbidity and in rare cases even mortality. The present review, which is based on the presentation of a typical case, discusses the current knowledge on the pathogenesis, clinical manifestations, diagnosis, prevention and therapy of β_2-microblobulin-associated amyloidosis.

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DIALYSIS AMYLOIDOSIS WITH MASSIVE POPLITEAL DEPOSITION OF Β2-Microglobulin AMYLOID

Cited by 22 publications

References 4 publications

Macroglossia and Amyloidoma of the Buttock: Evidence of Systemic Involvement in Dialysis Amyloid

Macroglossia and Amyloidoma of the Buttock: Evidence of Systemic Involvement in Dialysis Amyloid

Cubital tunnel syndrome caused by uremic tumoral calcinosis

Beta-2-Microglobulin-Associated Amyloidosis

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