Patient-reported physical and mental health status, along with disease-specific concerns ("quality of life") reported by patients, provide information about experience on dialysis that can help to improve patient care. Among prevalent hemodialysis (HD) patients, blacks have been shown to report higher health status and quality of life scores than whites, but whether similar race differences characterize incident patients who start regular dialysis is not known. Health status and quality of life, measured by the Kidney Disease Quality of Life-Short Form, reported by black men, black women, white men, and white women who initiated HD and peritoneal dialysis (PD) in the Dialysis Morbidity and Mortality Study (DMMS) Wave 2 were examined. After adjustment for patients' sociodemographic and clinical characteristics, the only race differences observed were that among HD patients, black women scored highest on the burden of kidney disease measure (lower perceived burden), and among PD patients, black men had the lowest satisfaction with care scores. It is possible that differences between blacks' and whites' reported health status and quality of life become more evident as patients' dialysis vintage increases, a hypothesis that requires following a well-characterized incident cohort over time. These findings add to existing evidence that minority patients on dialysis report less satisfaction with their care than do white patients, an important area for continued study.J M ultiple studies of prevalent patients who receive hemodialysis (HD) in the United States have found that blacks report better health status and quality of life compared with whites (1-10), but little evidence is available from studies of incident patients. The Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) study of patients who were on dialysis for approximately 3 mo found that nonwhites were less likely than whites to rate their care excellent overall (11), and both satisfaction with care and quality-of-life assessments summarize judgments that individuals make to describe their experiences of health and illness in relation to the expectations that they hold (12). The purpose of our study was to examine health status and quality of life, including satisfaction with care, reported early in treatment by black men, black women, white men, and white women in the Dialysis Morbidity and Mortality Study (DMMS) Wave 2. The DMMS Wave 2 included approximately equal numbers of patients who began peritoneal dialysis (PD) as well as patients who began HD, giving an opportunity to examine race and gender in relation to health status and quality of life reported by patients within both treatment modality groups. Our study therefore extends previous work on racial differences in prevalent HD patients' health status and quality of life by focusing on incident patients who start both HD and PD, as well as by considering the association of health status and quality of life with patients' gender as well as race.Potential explanations for obse...