Diameters of Nerve Fibers in Human Tooth Pulps

Graf, Wilhelm; Björlin, G

doi:10.14219/jada.archive.1951.0180

Cited by 53 publications

(8 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Here we report the number and size spectra of non-myelinated axons entering the apical radicular pulp of human premolars. Our finding that the premolars receive about 2000 non-myelinated axons is substantially higher than the values reported in two earlier studies (Graf and Bj6rlin 1951;Reader and Foreman 1981), which may be due to the inadequacy in methodology (Graf and Bj6rlin 1951) and the very limited numbers of teeth involved in those studies. However, the present data agree well with those reported on human mandibular first premolars (Johnsen et al 1983) and on permanent canines and incisors (Johnsen and Johns 1978).…”

Section: Discussioncontrasting

confidence: 82%

“…The available data relate mostly to rodent (Naftel et al 1994), feline (Johnsen and Karlsson 1974;Beasley and Holland 1978;Fried and Hildebrand 1981;Holland and Robinson 1983;Noga and Holland 1983;Hoffmeister and Schendel 1986), canine (Graf and Hjelmquist 1955;Hirvonen 1987), bovine (Graf and Hjelmquist 1955) and simian (Bueltmann et al 1972) teeth. Similar data on human intradental axons are scarce (Graf and Bj6rlin 1951;Johnsen and Johns 1978;Reader and Foreman 1981;Johnsen et al 1983). Most of these studies were conducted on small numbers of teeth and were not site-specific.…”

Section: Introductionmentioning

confidence: 93%

See 1 more Smart Citation

Number and size spectra of non-myelinated axons of human premolars

Nair

Schroeder

1995

Anat Embryol

View full text Add to dashboard Cite

The aim of this study was to determine the number and size of apical non-myelinated (C) axons of healthy human premolars. The material was derived from a large collection of specimens prepared for a previous quantitative investigation on the myelinated (A) axons of human premolars. A total of 16 teeth (six maxillary first and five each of mandibular first and second premolars), removed from adolescents for orthodontic reasons, were used. Root discs of about 0.6 mm thickness were prepared at about 2 mm cervical to the root apex and processed for light and electron microscopy. The number of non-myelinated axons was determined by taking a total census of such fibres that could be identified and reconstructed by standardized composite electron micrographs from each root disc. The measurement of axons was done on a statistically representative sample of axons (n = 1810) using an electronic image processing unit. The 16 teeth had an average of 2000 +/- 1023 non-myelinated axons at the juxta-apical level (range 534-3912). The average diameter of the non-myelinated axons was found to be 0.5 +/- 0.4 microns (range 0.05-2.4 microns).

show abstract

Section: Discussioncontrasting

confidence: 82%

Section: Introductionmentioning

confidence: 93%

Number and size spectra of non-myelinated axons of human premolars

Nair

Schroeder

1995

Anat Embryol

View full text Add to dashboard Cite

show abstract

“…However at the apex it appears that while A6 fibers predominate, a significant proportion (14% overall) are of wider diameter, although not enough to constitute a second mode. Some previous histological and physiological studies have reported larger myelinated fibers present in the pulp (Windle, 1927;Brashear, 1936;Pfaffman, 1939;Graf and Bjorlin, 1951;Graf and Hjelmquist, 1955;Matthews et al, 1959) although an equal number have shown them all within the A6 delta range (Brookhart et al, 1953;Funakoshi and Zotterman, 1963;Anderson and Perl, 1974;Johnsen and Karlsson, 1974;Uchizonno and Homma, 1959;Harris and Grif- fin, 1968). It has been suggested (Mumford, 1965) that sensations other than pain may be perceived upon stimulation of the tooth pulp.…”

Section: Discussionmentioning

confidence: 95%

“…Extensive branching and narrowing of axons within the root pulp may explain the large number and small size of axons in the coronal pulp. In support of this, studies at more apical levels of teeth in marmosets (Beultmann et al, 1972) and man (Reader and Foreman, 1981) show considerably fewer axons and in some cases the presence of axons with diameters greater than the A6 range (Windle, 1927;Brashear, 1936;Graf and Bjorlin, 1951;Fried and Hildebrand, 1981). The objective of this study was to count and measure axons that enter the apex of the cat's permanent mandibular canine.…”

mentioning

confidence: 86%

The number and size of axons at the apex of the cat's canine tooth

Holland

Robinson²

1983

Anat. Rec.

View full text Add to dashboard Cite

Using electron microscopy and morphometric analysis the number and size of axons entering the apex of the cat's mandibular canine tooth have been measured. The total number of axons varied from 761 to 1,903 between different animals but the maximum difference between right and left sides of the same animal was 353. From 56 to 79.6% of the axons were nonmyelinated; the difference in proportion between right and left sides never exceeded 6.4%. The mean circumference of myelinated axons ranged from 10.2 to 18.3 micrometers but again the right and left variation was much less and never exceeded 2 micrometers. In one tooth 38.8% of the myelinated axons were larger than 19 micrometers in circumference and thus outside the A delta range. The proportion was much smaller in other teeth but some "large" fibers were always present. Of all the nonmyelinated axons 19.7% showed some degree of axonal exposure to the extracellular space and 1.7% showed ax-oaxonal apposition. A small proportion of nonmyelinated axons showed evidence of apparent degeneration. Comparison of these data with those from studies at more coronal levels suggests that there is considerable branching and narrowing of fibers during their course through the dental pulp and that the degree of axonal exposure and apposition increases considerably. Some of the pulpal fibers are derived from larger axons than are normally associated with pain. The animal to animal variation in the parameters measured is considerable but right and left sides are similar.

show abstract

“…The nerve fibers of the hum an dental pulp show different diam eters (Brasiiear, 1936(Brasiiear, :K ing, 1938(Brasiiear, : H eed, 1955Vacek, 1969: Avery, 1971, and these fibers run either separately or together in a m ixed nerve (Vacek, 1969], which we confirmed. From the d ata presented nowadays, we believe th a t it is impossible to postulate a relationship between caliber ranges and nerve function | Brasiiear, 1936;H eld , 1955;Anneroth, 1968] because, from a physiological point of view, the dental innervation still entails prob lems th a t are far from being solved Graf [1951].…”

Section: Discussionmentioning

confidence: 99%